Immunizations in Chronic Kidney Disease and Kidney Transplantation

被引:11
作者
Babu, Tara M. [1 ,2 ]
Kotton, Camille N. [3 ]
机构
[1] Univ Washington, Div Allergy & Infect Dis, 908 Jefferson St,Suite 11NJ-1166, Seattle, WA 98104 USA
[2] Univ Rochester, Med Ctr, Div Infect Dis, Rochester, NY 14642 USA
[3] Harvard Med Sch, Massachusetts Gen Hosp, Infect Dis Div, Transplant & Immunocompromised Host Infect Dis, 55 Fruit St,Cox 5, Boston, MA 02114 USA
关键词
Vaccination; Chronic kidney disease; Kidney transplant; Immunization; SOLID-ORGAN TRANSPLANT; HEPATITIS-B-VACCINE; RANDOMIZED CONTROLLED-TRIAL; AGED; 19; YEARS; ADVISORY-COMMITTEE; INFLUENZA VACCINATION; UNITED-STATES; UPDATED RECOMMENDATIONS; PNEUMOCOCCAL VACCINE; HEMODIALYSIS-PATIENTS;
D O I
10.1007/s40506-021-00248-7
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Purpose of Review Infection is a significant cause of morbidity and mortality in both patients with chronic kidney disease (CKD) and in recipients of a kidney transplant (KT). We review the current data in patients with CKD, on dialysis, and in KT recipients to provide further guidance for clinicians regarding vaccine optimization in this patient population. Recent Findings This patient population remains under-vaccinated and thus more vulnerable to vaccine-preventable illness. Despite diminished responses to immunization in this population, significant protection is generally achieved. Vaccines are an important preventative tool and offer protection against infection. In the setting of suboptimal and waning immunity in this patient population, future studies are indicated to determine optimal vaccination regimens.
引用
收藏
页码:47 / 65
页数:19
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