A sensitive bioassay for chicken interleukin-18 based on the inducible release of preformed interferon-γ

被引：16
|
作者：
Puehler, F
Göbel, T
Breyer, U
Ohnemus, A
Staeheli, P
Kaspers, B
机构：
[1] Univ Munich, Inst Anim Physiol, D-80539 Munich, Germany
[2] Univ Freiburg, Dept Virol, D-79104 Freiburg, Germany
来源：
JOURNAL OF IMMUNOLOGICAL METHODS | 2003年 / 274卷 / 1-2期
关键词：
chicken; interleukin-18; interferon-gamma; bioassay;
D O I：
10.1016/S0022-1759(02)00515-X
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Conventional tests for measuring the biological activity of chicken interleukin (IL)-18 require primary chicken spleen cells. We now describe a sensitive bioassay that is based on interleukin-18 -induced release of interferon (IFN)-gamma by a permanent chicken cell line. In B19-2D8 cells, cytoplasmically stored interferon-gamma is quickly secreted in response to interleukin-18 exposure. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：229 / 232
页数：4
相关论文
共 50 条
  • [41] Thyrocyte interleukin-18 expression is up-regulated by interferon-γ and may contribute to thyroid destruction in Hashimoto's thyroiditis
    Liu, Zhe
    Wang, Haining
    Xiao, Wenhua
    Wang, Chen
    Liu, Guoqiang
    Hong, Tianpei
    INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, 2010, 91 (05) : 420 - 425
  • [42] Early Production of γ-Interferon in Clinical Malaria: Role of Interleukin-18 and Interleukin-12
    Torre, Donato
    CLINICAL INFECTIOUS DISEASES, 2009, 48 (10) : 1481 - 1482
  • [43] Congenital infections with Trypanosoma cruzi or Toxoplasma gondii are associated with decreased serum concentrations of interferon-γ and interleukin-18 but increased concentrations of interleukin-10
    Mayer, J. Patino
    Biancardi, M.
    Altcheh, J.
    Freilij, H.
    Weinke, T.
    Liesenfeld, O.
    ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, 2010, 104 (06): : 485 - 492
  • [44] Adjuvant effects of chicken interleukin-18 in avian Newcastle disease vaccine
    Hung, Li-Hsiang
    Li, Hsin-Pei
    Lien, Yi-Yang
    Wu, Mei-Li
    Chaung, Hso-Chi
    VACCINE, 2010, 28 (05) : 1148 - 1155
  • [45] Interferon-gamma, interleukin-18, monokine induced by interferon-gamma and interferon-gamma-inducible protein-10 in histiocytic necrotizing lymphadenitis
    Ohshima, K
    Haraoka, S
    Takahata, Y
    Takada, H
    Tsutiya, K
    Suzuki, K
    Suzumiya, J
    Kikuchi, M
    LEUKEMIA & LYMPHOMA, 2002, 43 (05) : 1115 - 1120
  • [46] Development of mouse monoclonal antibodies specific for chicken interleukin-18 (IL-18).
    Hong, Y. H.
    Lillehoj, H. S.
    Lee, S. H.
    Park, M. -S.
    LaBresh, J.
    Tompkins, D.
    Baldwin, C.
    JOURNAL OF DAIRY SCIENCE, 2010, 93 : 312 - 313
  • [47] Proinflammatory interferon-γ-inducing monokines (interleukin-12, interleukin-18, interieukin-15) -: serum profile in patients with systemic lupus erythematosus
    Robak, E
    Robak, T
    Wozniacka, A
    Zak-Prelich, M
    Sysa-Jedrzejowska, A
    Stepien, H
    EUROPEAN CYTOKINE NETWORK, 2002, 13 (03) : 364 - 368
  • [48] NUMERICAL MODELLING OF INTERLEUKIN-18 RELEASE FROM LIPID IMPLANTS
    Blagoeva, Rumiana
    Nedev, Assen
    COMPTES RENDUS DE L ACADEMIE BULGARE DES SCIENCES, 2011, 64 (06): : 875 - 882
  • [49] Expression modes of interferon-α inducible genes in sensitive and resistant human melanoma cells stimulated with regular and pegylated interferon-α
    Certa, U
    Wilhelm-Seiler, M
    Foser, S
    Broger, C
    Neeb, M
    GENE, 2003, 315 : 79 - 86
  • [50] Effect of histamine on intercellular adhesion molecule-1 expression and production of interferon-γ and interleukin-12 in mixed lymphocyte reaction stimulated with interleukin-18
    Itoh, H
    Takahashi, HK
    Iwagaki, H
    Yoshino, T
    Morimoto, Y
    Saito, S
    Yagi, T
    Akagi, T
    Nishibori, M
    Tanaka, N
    TRANSPLANTATION, 2002, 74 (06) : 864 - 870
12345