Synthesis of 2′-O-[(4"-O-stearoyl)-α-L-fucopyranosyl]thymidine:: A Shimofuridin analogue

被引：0

作者：

Ning, J ^{[1
]}

Kong, FZ ^{[1
]}

机构：

[1] Acad Sinica, Ecoenvironm Sci Res Ctr, Beijing 100085, Peoples R China

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1997年 / 7卷 / 23期

关键词：

D O I：

暂无

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A synthesis of the title compound has been achieved. The procedure involves a facile preparation of 1'-(3',5'-di-O-benzyl-A-D-ribofUranosyl)-thymine (8) with 1,2-anhydroribofuranose (7) as the glycosyl donor, stereoselective formation of a 1,2-cis (alpha) interglycoside bond with 4-O-stearoylated pyrimidin-2-yl 1 thio-beta-L-fucopyranoside (16) as the glycosyl donor. (C) 1997 Elsevier Science Ltd.

引用

页码：2941 / 2944

页数：4

共 11 条

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