Clinical Impact of Sarcopenia on Gastrointestinal Tumors

被引：3

作者：

Pereira, Ana ^{[1
]}

Pereira, Joaquim Costa ^{[2
]}

Martins, Sandra F. ^{[2
,3
,4
]}

机构：

[1] Braga Hosp, P-4710243 Braga, Portugal

[2] Braga Hosp, Surg Dept, Coloproctol Unit, P-4710243 Braga, Portugal

[3] Univ Minho, Sch Med, P-4710070 Braga, Portugal

[4] Life & Hlth Sci Res Inst ICVS 3Bs, PT Govt Associate Lab, P-4710070 Braga, Portugal

来源：

GASTROINTESTINAL DISORDERS | 2021年 / 3卷 / 01期

关键词：

gastrointestinal tumors; morbimortality; sarcopenia; COLORECTAL-CANCER RESECTION; BODY-COMPOSITION; NEOADJUVANT CHEMOTHERAPY; HEPATIC RESECTION; PROGNOSTIC VALUE; SKELETAL-MUSCLE; SOLID TUMORS; OUTCOMES; FRAILTY; TOMOGRAPHY;

D O I：

10.3390/gidisord3010006

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Preoperative risk stratification in cancer surgery is important to improve treatment and outcome. Sarcopenia is defined by progressive and generalized loss of skeletal muscle mass and strength and is now getting attention as a poor prognostic factor. The purpose of this review was to explore the impact of sarcopenia on short and long-term outcomes in patients undergoing surgical resection of gastrointestinal tumors. Recent studies suggest that sarcopenia contributes to postoperative complications and overall survival. The relatively simple evaluability, as well as its modifiable nature, provides an intriguing potential for sarcopenia to be included in standard preoperative clinical evaluation. Such evaluations can provide physicians with important information to target high-risk individuals with prophylactic measures and eventually improve surgical outcomes.

引用

页码：51 / 60

页数：10

共 60 条

[1] Are there any benefits of exercise training in cancer cachexia? [J].

Argiles, Josep M. ;

Busquets, Silvia ;

Lopez-Soriano, Francisco J. ;

Costelli, Paola ;

Penna, Fabio .

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2012, 3 (02) :73-76

[2] Marked changes in body composition following neoadjuvant chemotherapy for oesophagogastric cancer [J].

Awad, Sherif ;

Tan, Benjamin H. ;

Cui, Helen ;

Bhalla, Ashish ;

Fearon, Kenneth C. H. ;

Parsons, Simon L. ;

Caton, James A. ;

Lobo, Dileep N. .

CLINICAL NUTRITION, 2012, 31 (01) :74-77

[3] Myostatin antibody (LY2495655) in older weak fallers: a proof-of-concept, randomised, phase 2 trial [J].

Becker, Clemens ;

Lord, Stephen R. ;

Studenski, Stephanie A. ;

Warden, Stuart J. ;

Fielding, Roger A. ;

Recknor, Christopher P. ;

Hochberg, Marc C. ;

Ferrari, Serge L. ;

Blain, Hubert ;

Binder, Ellen F. ;

Rolland, Yves ;

Poiraudeau, Serge ;

Benson, Charles T. ;

Myers, Stephen L. ;

Hu, Leijun ;

Ahmad, Qasim I. ;

Pacuch, Kelli R. ;

Gomez, Elisa V. ;

Benichou, Olivier .

LANCET DIABETES & ENDOCRINOLOGY, 2015, 3 (12) :948-957

[4] Prognostic Value of Computed Tomography: Measured Parameters of Body Composition in Primary Operable Gastrointestinal Cancers [J].

Black, Douglas ;

Mackay, Craig ;

Ramsay, George ;

Hamoodi, Zaid ;

Nanthakumaran, Shayanthan ;

Park, Kenneth G. M. ;

Loudon, Malcolm A. ;

Richards, Colin H. .

ANNALS OF SURGICAL ONCOLOGY, 2017, 24 (08) :2241-2251

[5] Prevalence of sarcopenia in older patients with colorectal cancer [J].

Broughman, James R. ;

Williams, Grant R. ;

Deal, Allison M. ;

Yu, Hyeon ;

Nyrop, Kirsten A. ;

Alston, Shani M. ;

Gordon, Brittaney-Belle ;

Sanoff, Hanna K. ;

Muss, Hyman B. .

JOURNAL OF GERIATRIC ONCOLOGY, 2015, 6 (06) :442-445

[6] Sarcopenia in Asia: Consensus Report of the Asian Working Group for Sarcopenia [J].

Chen, Liang-Kung ;

Liu, Li-Kuo ;

Woo, Jean ;

Assantachai, Prasert ;

Auyeung, Tung-Wai ;

Bahyah, Kamaruzzaman Shahrul ;

Chou, Ming-Yueh ;

Chen, Liang-Yu ;

Hsu, Pi-Shan ;

Krairit, Orapitchaya ;

Lee, Jenny S. W. ;

Lee, Wei-Ju ;

Lee, Yunhwan ;

Liang, Chih-Kuang ;

Limpawattana, Panita ;

Lin, Chu-Sheng ;

Peng, Li-Ning ;

Satake, Shosuke ;

Suzuki, Takao ;

Won, Chang Won ;

Wu, Chih-Hsing ;

Wu, Si-Nan ;

Zhang, Teimei ;

Zeng, Ping ;

Akishita, Masahiro ;

Arai, Hidenori .

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2014, 15 (02) :95-101

[7] Prevalence of sarcopenia among healthy ambulatory subjects: the sarcopenia begins from 45 years [J].

Cherin, Patrick ;

Voronska, Elena ;

Fraoucene, Nadia ;

de Jaeger, Christophe .

AGING CLINICAL AND EXPERIMENTAL RESEARCH, 2014, 26 (02) :137-146

[8] Frailty and sarcopenia: definitions and outcome parameters [J].

Cooper, C. ;

Dere, W. ;

Evans, W. ;

Kanis, J. A. ;

Rizzoli, R. ;

Sayer, A. A. ;

Sieber, C. C. ;

Kaufman, J-M. ;

van Kan, G. Abellan ;

Boonen, S. ;

Adachi, J. ;

Mitlak, B. ;

Tsouderos, Y. ;

Rolland, Y. ;

Reginster, J-Y. L. .

OSTEOPOROSIS INTERNATIONAL, 2012, 23 (07) :1839-1848

[9] Sarcopenia: European consensus on definition and diagnosis [J].

Cruz-Jentoft, Alfonso J. ;

Baeyens, Jean Pierre ;

Bauer, Juergen M. ;

Boirie, Yves ;

Cederholm, Tommy ;

Landi, Francesco ;

Martin, Finbarr C. ;

Michel, Jean-Pierre ;

Rolland, Yves ;

Schneider, Stephane M. ;

Topinkova, Eva ;

Vandewoude, Maurits ;

Zamboni, Mauro .

AGE AND AGEING, 2010, 39 (04) :412-423

[10] The selective androgen receptor modulator GTx-024 (enobosarm) improves lean body mass and physical function in healthy elderly men and postmenopausal women: results of a double-blind, placebo-controlled phase II trial [J].

Dalton, James T. ;

Barnette, Kester G. ;

Bohl, Casey E. ;

Hancock, Michael L. ;

Rodriguez, Domingo ;

Dodson, Shontelle T. ;

Morton, Ronald A. ;

Steiner, Mitchell S. .

JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE, 2011, 2 (03) :153-161

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