Point of care testing assay for haemoglobin A1c on In2it™ during paediatric diabetic consultation

被引：1

作者：

Marzullo, C. ^{[1
]}

Minery, M. ^{[1
]}

Guemazi, F. ^{[2
]}

Stojiljkovic, D. ^{[2
]}

Benoit, M. ^{[2
]}

机构：

[1] Hop Emile Muller, Biochim Lab, F-68100 Mulhouse, France

[2] Hop Emile Muller, Serv Pediat, F-68100 Mulhouse, France

来源：

IMMUNO-ANALYSE & BIOLOGIE SPECIALISEE | 2010年 / 25卷 / 01期

关键词：

Haemoglobin A1c; Point of care testing; In2it (TM);

D O I：

10.1016/j.immbio.2010.01.003

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The In2it (TM) is a POCT testing system for haemoglobin A1c (Hb(A1c)) assay using a boronate affinity method. We evaluated its analytical qualities, practicability and the effect of this assay on patient follow-up, when using during a paediatric diabetic consultation. Imprecision was good (between-run CV less than 4%). Results are well-correlated with those obtained on D10 (TM), high-pressure liquid chromatography analyser (r = 0.978). Bland-Altman graph showed good agreement between the two methods. HbS did not interfere, but it was not identified. HbC induced 1% overestimation of result. Practicability was good. However the software could be improved. Knowledge of Hb(A1c) value during consultation permits a better adaptation of therapy and improves motivation and comfort of the patient. This activity has to be controlled according the Guide de bonne execution des analyses de biologie medicate (GBEA) and needs a good partnership between biologists and clinical staffs. (C) 2010 Elsevier Masson SAS. All rights reserved.

引用

页码：34 / 37

页数：4

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