Novel axially carborane-cage substituted silicon phthalocyanine photosensitizer; synthesis, characterization and photophysicochemical properties

被引：80

作者：

Atmaca, Goknur Yasa ^{[1
]}

Dizman, Cemil ^{[2
]}

Eren, Tarik ^{[1
]}

Erdogmus, Ali ^{[1
]}

机构：

[1] Yildiz Tekn Univ, Dept Chem, TR-34210 Istanbul, Turkey

[2] TUBITAK Marmara Res Ctr, Inst Chem, TR-41470 Kocaeli, Turkey

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2015年 / 137卷

关键词：

Phthalocyanine; Silicon; Carborane; Photochemistry; Photophysic; VITRO PHOTODYNAMIC ACTIVITIES; POLY(ETHYLENE GLYCOL) CHAINS; BOVINE SERUM-ALBUMIN; METAL PHTHALOCYANINES; ZINC PHTHALOCYANINES; COMPLEXATION; AGGREGATION; PDT;

D O I：

10.1016/j.saa.2014.08.035

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

The novel axially dicarborane substituted silicon (IV) (SiPc-DC) phthalocyanine was synthesized by treating silicon phthalocyanine dichloride SiPc(Cl)(2) (SiPc) with o-Carborane monool. The compound was characterized by mass spectrometry, UV Vis, FT-IR, H-1 and B-11 Nuclear Magnetic Resonance Spectroscopy (NMR). Spectral, photophysical (fluorescence quantum yield) and photochemical (singlet oxygen (Phi(Delta)) and photodegradation quantum yield (Phi(d))) properties of the complex were reported in different solutions (Dimethyl sulfoxide (DMSO), Dimethylformamide (DMF) and Toluene). The results of spectral measurements showed that both SiPc and carborane cage can have potential to be used as sensitizers in photodynamic therapy (PDT) and boron neutron capture therapy (BNCT) by their singlet oxygen efficiencies (Phi(Delta)= 0.41, 0.39). (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：244 / 249

页数：6

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