The tail end of membrane insertion

被引:5
|
作者
Mandon, Elisabet C. [1 ]
Gilmore, Reid [1 ]
机构
[1] Univ Massachusetts, Sch Med, Dept Mol Pharmacol & Biochem, Worcester, MA 01605 USA
关键词
D O I
10.1016/j.cell.2007.03.001
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Many membrane proteins are inserted into cellular membranes via a carboxy-terminal tail-anchor segment, but the mechanism of insertion is poorly understood. In this issue of Cell, Stefanovic and Hegde (2007) report the identification and initial characterization of a soluble ATP-dependent receptor for the insertion of newly synthesized tail-anchored membrane proteins.
引用
收藏
页码:1031 / 1032
页数:2
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