Protocol biopsies after kidney transplantation

被引：31

作者：

Böhmig, GA

Regele, H

Hörl, WH

机构：

[1] Univ Vienna, Dept Internal Med 3, Div Nephrol & Dialysis, A-1090 Vienna, Austria

[2] Univ Vienna, Clin Inst Pathol, A-1090 Vienna, Austria

来源：

TRANSPLANT INTERNATIONAL | 2005年 / 18卷 / 02期

关键词：

chronic allograft nephropathy; kidney transplantation; protocol biopsy; subclinical rejection;

D O I：

10.1111/j.1432-2277.2004.00020.x

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Numerous studies have investigated features of allograft injury in renal biopsies obtained in stable kidney transplants. Evaluation of protocol biopsies has revealed a considerably high prevalence of subclinical acute rejection (SAR) and chronic allograft nephropathy (CAN) already in early phases after transplantation. The meanwhile well-established association of SAR and CAN in protocol biopsy with long-term allograft failure and the finding of superior allograft outcome after treatment of SAR in a randomized prospective study may point to clinical relevance of this procedure. In this review, potential benefits and risks associated with kidney allograft biopsy in stable renal transplant recipients are discussed.

引用

页码：131 / 139

页数：9

共 55 条

[1] Molecular and structural consequences of early renal allograft injury [J].

Baboolal, K ;

Jones, GA ;

Janezic, A ;

Griffiths, DR ;

Jurewicz, WA .

KIDNEY INTERNATIONAL, 2002, 61 (02) :686-696

[2] Differential effects of cyclosporin and tacrolimus on the expression of fibrosis-associated genes in isolated glomeruli from renal transplants [J].

Bicknell, GR ;

Williams, ST ;

Shaw, JA ;

Pringle, JH ;

Furness, PN ;

Nicholson, ML .

BRITISH JOURNAL OF SURGERY, 2000, 87 (11) :1569-1575

[3] Diagnosis and treatment of antibody-mediated kidney allograft rejection [J].

Böhmig, G ;

Regele, H .

TRANSPLANT INTERNATIONAL, 2003, 16 (11) :773-787

[4]

BURDICK JF, 1984, TRANSPLANT P, V16, P1580

[5] CHARACTERISTICS OF EARLY ROUTINE RENAL-ALLOGRAFT BIOPSIES [J].

BURDICK, JF ;

BESCHORNER, WE ;

SMITH, WJ ;

MCGRAW, D ;

BENDER, WL ;

WILLIAMS, GM ;

SOLEZ, K .

TRANSPLANTATION, 1984, 38 (06) :679-684

[6]

DIMENY E, 1995, CLIN TRANSPLANT, V9, P79

[7]

Fiebeler A, 2002, J AM SOC NEPHROL, V13, p568A

[8] Protocol biopsy of the stable renal transplant:: A multicenter study of methods and complication rates [J].

Furness, PN ;

Philpott, CM ;

Chorbadjian, MT ;

Nicholson, ML ;

Bosmans, JL ;

Corthouts, BL ;

Bogers, JJPM ;

Schwarz, A ;

Gwinner, W ;

Haller, H ;

Mengel, M ;

Seron, D ;

Moreso, F ;

Cañas, C .

TRANSPLANTATION, 2003, 76 (06) :969-973

[9] Subclinical rejection in tacrolimus-treated renal transplant recipients [J].

Gloor, JM ;

Cohen, AJ ;

Lager, DJ ;

Grande, JP ;

Fidler, ME ;

Velosa, JA ;

Larson, TS ;

Schwab, TR ;

Griffin, MD ;

Prieto, M ;

Nyberg, SL ;

Sterioff, S ;

Kremers, WK ;

Stegall, MD .

TRANSPLANTATION, 2002, 73 (12) :1965-1968

[10] Renal transplantation: Can we reduce calcineurin inhibitor/stop steroids? evidence based on protocol biopsy findings [J].

Gotti, E ;

Perico, N ;

Perna, A ;

Gaspari, F ;

Cattaneo, D ;

Caruso, R ;

Ferrari, S ;

Stucchi, N ;

Marchetti, G ;

Abbate, M ;

Remuzzi, G .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2003, 14 (03) :755-766

← 1 2 3 4 5 6 →