Plasma-induced polymerisation of hydrophilic coatings onto macroporous hydrophobic scaffolds

被引：26

作者：

Aroca, A. Serrano

Pradas, M. Monleon

Ribelles, J. L. Gomez

机构：

[1] Univ Politecn Valencia, Ctr Biomat, Valencia 46022, Spain

[2] Ctr Invest Principe Felipe, Valencia 46013, Spain

来源：

POLYMER | 2007年 / 48卷 / 07期

关键词：

plasma-induced polymerisation; hydrogel; water sorption;

D O I：

10.1016/j.polymer.2007.02.017

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Macroporous poly(methyl methacrylate) scaffolds with a well-interconnected pore architecture were coated with poly(2-hydroxyethyl acrylate) following a particular protocol of plasma-induced polymerisation. Plasma-polymerised PHEA (plPHEA) was grafted onto two macroporous poly(methyl methacrylate) scaffolds with varying cross-linking density showing significant differences in the interpenetration of the coating and the PMMA substrate. Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM) proved that the surface of the pore structure in the whole volume of the sample was coated. The stability of the plPHEA coating was studied by extraction with distilled water at different temperatures. After the extraction, these samples were observed by SEM and analysed by differential scanning calorimetry (DSC) and FTIR showing that only in very drastic conditions plPHEA suffers hydrolytic degradation. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：2071 / 2078

页数：8

共 21 条

[1]

Amass W, 1998, POLYM INT, V47, P89, DOI 10.1002/(SICI)1097-0126(1998100)47:2<89::AID-PI86>3.0.CO

[2]

2-F

[3]

AROCA AS, IN PRESS COLL POLYM

[4]

DENES F, 1994, APPL POLYM SYMP SER, V54, P55

[5] Acrylic scaffolds with interconnected spherical pores and controlled hydrophilicity for tissue engineering [J].

Diego, RB ;

Olmedilla, MP ;

Aroca, AS ;

Ribelles, JLG ;

Pradas, MM ;

Ferrer, GG ;

Sánchez, MS .

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2005, 16 (08) :693-698

[6]

DIMITRIU S, 1994, POLYM BIOMATERIALS

[7]

Dusek K., 1967, Journal o f Polymer Science, P1289

[8]

Dusek K., 1971, POLYM NETWORKS STRUC

[9]

Gaur S., 2000, 43 ANN TECHN C P DEN

[10] HUMIDITY FIXED-POINTS OF BINARY SATURATED AQUEOUS-SOLUTIONS [J].

GREENSPAN, L .

JOURNAL OF RESEARCH OF THE NATIONAL BUREAU OF STANDARDS SECTION A-PHYSICS AND CHEMISTRY, 1977, 81 (01) :89-96

← 1 2 3 →