Quantitative electron density characterization of soft tissue substitute plastic materials using grating-based x-ray phase-contrast imaging

被引:14
作者
Sarapata, A. [1 ,2 ]
Chabior, M. [1 ,2 ]
Cozzini, C. [3 ]
Sperl, J. I. [3 ]
Beque, D. [3 ]
Langner, O. [4 ]
Coman, J. [4 ]
Zanette, I. [1 ,2 ]
Ruiz-Yaniz, M. [1 ,2 ,5 ]
Pfeiffer, F. [1 ,2 ]
机构
[1] Tech Univ Munich, Lehrstuhl Biomed Phys, Dept Phys, D-85748 Garching, Germany
[2] Tech Univ Munich, Inst Med Tech, D-85748 Garching, Germany
[3] GE Global Res, D-85748 Garching, Germany
[4] QRM GmbH, Mohrendorf, Germany
[5] European Synchrotron Radiat Facil, F-38043 Grenoble, France
基金
欧洲研究理事会;
关键词
TALBOT INTERFEROMETRY; BREAST-TISSUE; TOMOGRAPHY; CT; RADIOTHERAPY;
D O I
10.1063/1.4898052
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
Many scientific research areas rely on accurate electron density characterization of various materials. For instance in X-ray optics and radiation therapy, there is a need for a fast and reliable technique to quantitatively characterize samples for electron density. We present how a precise measurement of electron density can be performed using an X-ray phase-contrast grating interferometer in a radiographic mode of a homogenous sample in a controlled geometry. A batch of various plastic materials was characterized quantitatively and compared with calculated results. We found that the measured electron densities closely match theoretical values. The technique yields comparable results between a monochromatic and a polychromatic X-ray source. Measured electron densities can be further used to design dedicated X-ray phase contrast phantoms and the additional information on small angle scattering should be taken into account in order to exclude unsuitable materials. (C) 2014 AIP Publishing LLC.
引用
收藏
页数:7
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