Hydroa vacciniforme-like cutaneous T-cell lymphoma in a child A case report

被引：4
作者：
Li, Jingyi [3 ]
Zan, Yiheng [1 ,2 ]
Liu, Hongjie [3 ]
Liu, Hanmin [1 ,2 ]
Chen, Lina [1 ,2 ]
机构：
[1] Sichuan Univ, West China Univ Hosp 2, Dept Pediat, Chengdu, Sichuan, Peoples R China
[2] Sichuan Univ, Minist Educ, Key Lab Birth Defects & Related Dis Women & Child, Chengdu, Sichuan, Peoples R China
[3] Sichuan Univ, West China Hosp, Dept Dermatol, Chengdu, Sichuan, Peoples R China
来源：
MEDICINE | 2018年 / 97卷 / 15期
基金：
中国国家自然科学基金;
关键词：
Epstein-Barr virus; hydroa vacciniforme-like T-cell lymphoma; skin; LYMPHOPROLIFERATIVE DISORDERS; DISEASES;
D O I：
10.1097/MD.0000000000010319
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Rationale: Hydroa vacciniforme (HV)-like T-cell lymphoma is a rare malignancy in childhood associated with Epstein-Barr virus infection. Patient concerns: A 6-year old girl presented with complaint of 3-year history of recurrent skin lesions, 3 months of fever accompanied by cough for 8 days. Diagnoses: Skin biopsy revealed a HV-like lymphoma presentation and positive signals of EBER were detected by in situ hybridization. TCR-gamma gene monoclonal rearrangement was present. A HV-like cutaneous T-cell lymphoma was diagnosed. Interventions: The girl was treated with cyclosporine and CHOP. Outcomes: The girl's condition had been stable for 6 months. Lessons: Our case highlights the necessity for taking the HV-like lymphoma as a differential diagnosis especially when a patient manifests as recurrent skin lesions accompanied by systemic involvement.
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页数：4
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