Attack of the clones

被引：18

作者：

Govindan, Ramaswamy ^{[1
,2
]}

机构：

[1] Washington Univ, Sch Med, Dept Med, St Louis, MO 63110 USA

[2] Washington Univ, Sch Med, Alvin J Siteman Canc Ctr, St Louis, MO 63110 USA

来源：

SCIENCE | 2014年 / 346卷 / 6206期

关键词：

ACUTE MYELOID-LEUKEMIA; LUNG-CANCER; EVOLUTION; ARCHITECTURE; THERAPY;

D O I：

10.1126/science.1259926

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

[No abstract available]

引用

页码：169 / 170

页数：2

共 14 条

[1] Genetic variegation of clonal architecture and propagating cells in leukaemia [J].

Anderson, Kristina ;

Lutz, Christoph ;

van Delft, Frederik W. ;

Bateman, Caroline M. ;

Guo, Yanping ;

Colman, Susan M. ;

Kempski, Helena ;

Moorman, Anthony V. ;

Titley, Ian ;

Swansbury, John ;

Kearney, Lyndal ;

Enver, Tariq ;

Greaves, Mel .

NATURE, 2011, 469 (7330) :356-+

[2] Comprehensive molecular profiling of lung adenocarcinoma [J].

Collisson, Eric A. ;

Campbell, Joshua D. ;

Brooks, Angela N. ;

Berger, Alice H. ;

Lee, William ;

Chmielecki, Juliann ;

Beer, David G. ;

Cope, Leslie ;

Creighton, Chad J. ;

Danilova, Ludmila ;

Ding, Li ;

Getz, Gad ;

Hammerman, Peter S. ;

Hayes, D. Neil ;

Hernandez, Bryan ;

Herman, James G. ;

Heymach, John V. ;

Jurisica, Igor ;

Kucherlapati, Raju ;

Kwiatkowski, David ;

Ladanyi, Marc ;

Robertson, Gordon ;

Schultz, Nikolaus ;

Shen, Ronglai ;

Sinha, Rileen ;

Sougnez, Carrie ;

Tsao, Ming-Sound ;

Travis, William D. ;

Weinstein, John N. ;

Wigle, Dennis A. ;

Wilkerson, Matthew D. ;

Chu, Andy ;

Cherniack, Andrew D. ;

Hadjipanayis, Angela ;

Rosenberg, Mara ;

Weisenberger, Daniel J. ;

Laird, Peter W. ;

Radenbaugh, Amie ;

Ma, Singer ;

Stuart, Joshua M. ;

Byers, Lauren Averett ;

Baylin, Stephen B. ;

Govindan, Ramaswamy ;

Meyerson, Matthew ;

Rosenberg, Mara ;

Gabriel, Stacey B. ;

Cibulskis, Kristian ;

Sougnez, Carrie ;

Kim, Jaegil ;

Stewart, Chip .

NATURE, 2014, 511 (7511) :543-550

[3] Spatial and temporal diversity in genomic instability processes defines lung cancer evolution [J].

de Bruin, Elza C. ;

McGranahan, Nicholas ;

Mitter, Richard ;

Salm, Max ;

Wedge, David C. ;

Yates, Lucy ;

Jamal-Hanjani, Mariam ;

Shafi, Seema ;

Murugaesu, Nirupa ;

Rowan, Andrew J. ;

Groenroos, Eva ;

Muhammad, Madiha A. ;

Horswell, Stuart ;

Gerlinger, Marco ;

Varela, Ignacio ;

Jones, David ;

Marshall, John ;

Voet, Thierry ;

Van Loo, Peter ;

Rassl, Doris M. ;

Rintoul, Robert C. ;

Janes, Sam M. ;

Lee, Siow-Ming ;

Forster, Martin ;

Ahmad, Tanya ;

Lawrence, David ;

Falzon, Mary ;

Capitanio, Arrigo ;

Harkins, Timothy T. ;

Lee, Clarence C. ;

Tom, Warren ;

Teefe, Enock ;

Chen, Shann-Ching ;

Begum, Sharmin ;

Rabinowitz, Adam ;

Phillimore, Benjamin ;

Spencer-Dene, Bradley ;

Stamp, Gordon ;

Szallasi, Zoltan ;

Matthews, Nik ;

Stewart, Aengus ;

Campbell, Peter ;

Swanton, Charles .

SCIENCE, 2014, 346 (6206) :251-256

[4] Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing [J].

Ding, Li ;

Ley, Timothy J. ;

Larson, David E. ;

Miller, Christopher A. ;

Koboldt, Daniel C. ;

Welch, John S. ;

Ritchey, Julie K. ;

Young, Margaret A. ;

Lamprecht, Tamara ;

McLellan, Michael D. ;

McMichael, Joshua F. ;

Wallis, John W. ;

Lu, Charles ;

Shen, Dong ;

Harris, Christopher C. ;

Dooling, David J. ;

Fulton, Robert S. ;

Fulton, Lucinda L. ;

Chen, Ken ;

Schmidt, Heather ;

Kalicki-Veizer, Joelle ;

Magrini, Vincent J. ;

Cook, Lisa ;

McGrath, Sean D. ;

Vickery, Tammi L. ;

Wendl, Michael C. ;

Heath, Sharon ;

Watson, Mark A. ;

Link, Daniel C. ;

Tomasson, Michael H. ;

Shannon, William D. ;

Payton, Jacqueline E. ;

Kulkarni, Shashikant ;

Westervelt, Peter ;

Walter, Matthew J. ;

Graubert, Timothy A. ;

Mardis, Elaine R. ;

Wilson, Richard K. ;

DiPersio, John F. .

NATURE, 2012, 481 (7382) :506-510

[5] Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing [J].

Gerlinger, Marco ;

Horswell, Stuart ;

Larkin, James ;

Rowan, Andrew J. ;

Salm, Max P. ;

Varela, Ignacio ;

Fisher, Rosalie ;

McGranahan, Nicholas ;

Matthews, Nicholas ;

Santos, Claudio R. ;

Martinez, Pierre ;

Phillimore, Benjamin ;

Begum, Sharmin ;

Rabinowitz, Adam ;

Spencer-Dene, Bradley ;

Gulati, Sakshi ;

Bates, Paul A. ;

Stamp, Gordon ;

Pickering, Lisa ;

Gore, Martin ;

Nicol, David L. ;

Hazell, Steven ;

Futreal, P. Andrew ;

Stewart, Aengus ;

Swanton, Charles .

NATURE GENETICS, 2014, 46 (03) :225-+

[6] Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers [J].

Govindan, Ramaswamy ;

Ding, Li ;

Griffith, Malachi ;

Subramanian, Janakiraman ;

Dees, Nathan D. ;

Kanchi, Krishna L. ;

Maher, Christopher A. ;

Fulton, Robert ;

Fulton, Lucinda ;

Wallis, John ;

Chen, Ken ;

Walker, Jason ;

McDonald, Sandra ;

Bose, Ron ;

Ornitz, David ;

Xiong, Donghai ;

You, Ming ;

Dooling, David J. ;

Watson, Mark ;

Mardis, Elaine R. ;

Wilson, Richard K. .

CELL, 2012, 150 (06) :1121-1134

[7] Comprehensive genomic characterization of squamous cell lung cancers [J].

Hammerman, Peter S. ;

Lawrence, Michael S. ;

Voet, Douglas ;

Jing, Rui ;

Cibulskis, Kristian ;

Sivachenko, Andrey ;

Stojanov, Petar ;

McKenna, Aaron ;

Lander, Eric S. ;

Gabriel, Stacey ;

Getz, Gad ;

Sougnez, Carrie ;

Imielinski, Marcin ;

Helman, Elena ;

Hernandez, Bryan ;

Pho, Nam H. ;

Meyerson, Matthew ;

Chu, Andy ;

Chun, Hye-Jung E. ;

Mungall, Andrew J. ;

Pleasance, Erin ;

Robertson, A. Gordon ;

Sipahimalani, Payal ;

Stoll, Dominik ;

Balasundaram, Miruna ;

Birol, Inanc ;

Butterfield, Yaron S. N. ;

Chuah, Eric ;

Coope, Robin J. N. ;

Corbett, Richard ;

Dhalla, Noreen ;

Guin, Ranabir ;

Hirst, Anhe Carrie ;

Hirst, Martin ;

Holt, Robert A. ;

Lee, Darlene ;

Li, Haiyan I. ;

Mayo, Michael ;

Moore, Richard A. ;

Mungall, Karen ;

Nip, Ka Ming ;

Olshen, Adam ;

Schein, Jacqueline E. ;

Slobodan, Jared R. ;

Tam, Angela ;

Thiessen, Nina ;

Varhol, Richard ;

Zeng, Thomas ;

Zhao, Yongjun ;

Jones, Steven J. M. .

NATURE, 2012, 489 (7417) :519-525

[8] Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma [J].

Johnson, Brett E. ;

Mazor, Tali ;

Hong, Chibo ;

Barnes, Michael ;

Aihara, Koki ;

McLean, Cory Y. ;

Fouse, Shaun D. ;

Yamamoto, Shogo ;

Ueda, Hiroki ;

Tatsuno, Kenji ;

Asthana, Saurabh ;

Jalbert, Llewellyn E. ;

Nelson, Sarah J. ;

Bollen, Andrew W. ;

Gustafson, W. Clay ;

Charron, Elise ;

Weiss, William A. ;

Smirnov, Ivan V. ;

Song, Jun S. ;

Olshen, Adam B. ;

Cha, Soonmee ;

Zhao, Yongjun ;

Moore, Richard A. ;

Mungall, Andrew J. ;

Jones, Steven J. M. ;

Hirst, Martin ;

Marra, Marco A. ;

Saito, Nobuhito ;

Aburatani, Hiroyuki ;

Mukasa, Akitake ;

Berger, Mitchel S. ;

Chang, Susan M. ;

Taylor, Barry S. ;

Costello, Joseph F. .

SCIENCE, 2014, 343 (6167) :189-193

[9] Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia [J].

Landau, Dan A. ;

Carter, Scott L. ;

Stojanov, Petar ;

McKenna, Aaron ;

Stevenson, Kristen ;

Lawrence, Michael S. ;

Sougnez, Carrie ;

Stewart, Chip ;

Sivachenko, Andrey ;

Wang, Lili ;

Wan, Youzhong ;

Zhang, Wandi ;

Shukla, Sachet A. ;

Vartanov, Alexander ;

Fernandes, Stacey M. ;

Saksena, Gordon ;

Cibulskis, Kristian ;

Tesar, Bethany ;

Gabriel, Stacey ;

Hacohen, Nir ;

Meyerson, Matthew ;

Lander, Eric S. ;

Neuberg, Donna ;

Brown, Jennifer R. ;

Getz, Gad ;

Wu, Catherine J. .

CELL, 2013, 152 (04) :714-726

[10] Widespread Genetic Heterogeneity in Multiple Myeloma: Implications for Targeted Therapy [J].

Lohr, Jens G. ;

Stojanov, Petar ;

Carter, Scott L. ;

Cruz-Gordillo, Peter ;

Lawrence, Michael S. ;

Auclair, Daniel ;

Sougnez, Carrie ;

Knoechel, Birgit ;

Gould, Joshua ;

Saksena, Gordon ;

Cibulskis, Kristian ;

McKenna, Aaron ;

Chapman, Michael A. ;

Straussman, Ravid ;

Levy, Joan ;

Perkins, Louise M. ;

Keats, Jonathan J. ;

Schumacher, Steven E. ;

Rosenberg, Mara ;

Getz, Gad ;

Golub, Todd R. .

CANCER CELL, 2014, 25 (01) :91-101

← 1 2 →

共 14 条

[1] Genetic variegation of clonal architecture and propagating cells in leukaemia [J].

Anderson, Kristina ;

Lutz, Christoph ;

van Delft, Frederik W. ;

Bateman, Caroline M. ;

Guo, Yanping ;

Colman, Susan M. ;

Kempski, Helena ;

Moorman, Anthony V. ;

Titley, Ian ;

Swansbury, John ;

Kearney, Lyndal ;

Enver, Tariq ;

Greaves, Mel .

NATURE, 2011, 469 (7330) :356-+

[2] Comprehensive molecular profiling of lung adenocarcinoma [J].

Collisson, Eric A. ;

Campbell, Joshua D. ;

Brooks, Angela N. ;

Berger, Alice H. ;

Lee, William ;

Chmielecki, Juliann ;

Beer, David G. ;

Cope, Leslie ;

Creighton, Chad J. ;

Danilova, Ludmila ;

Ding, Li ;

Getz, Gad ;

Hammerman, Peter S. ;

Hayes, D. Neil ;

Hernandez, Bryan ;

Herman, James G. ;

Heymach, John V. ;

Jurisica, Igor ;

Kucherlapati, Raju ;

Kwiatkowski, David ;

Ladanyi, Marc ;

Robertson, Gordon ;

Schultz, Nikolaus ;

Shen, Ronglai ;

Sinha, Rileen ;

Sougnez, Carrie ;

Tsao, Ming-Sound ;

Travis, William D. ;

Weinstein, John N. ;

Wigle, Dennis A. ;

Wilkerson, Matthew D. ;

Chu, Andy ;

Cherniack, Andrew D. ;

Hadjipanayis, Angela ;

Rosenberg, Mara ;

Weisenberger, Daniel J. ;

Laird, Peter W. ;

Radenbaugh, Amie ;

Ma, Singer ;

Stuart, Joshua M. ;

Byers, Lauren Averett ;

Baylin, Stephen B. ;

Govindan, Ramaswamy ;

Meyerson, Matthew ;

Rosenberg, Mara ;

Gabriel, Stacey B. ;

Cibulskis, Kristian ;

Sougnez, Carrie ;

Kim, Jaegil ;

Stewart, Chip .

NATURE, 2014, 511 (7511) :543-550

[3] Spatial and temporal diversity in genomic instability processes defines lung cancer evolution [J].

de Bruin, Elza C. ;

McGranahan, Nicholas ;

Mitter, Richard ;

Salm, Max ;

Wedge, David C. ;

Yates, Lucy ;

Jamal-Hanjani, Mariam ;

Shafi, Seema ;

Murugaesu, Nirupa ;

Rowan, Andrew J. ;

Groenroos, Eva ;

Muhammad, Madiha A. ;

Horswell, Stuart ;

Gerlinger, Marco ;

Varela, Ignacio ;

Jones, David ;

Marshall, John ;

Voet, Thierry ;

Van Loo, Peter ;

Rassl, Doris M. ;

Rintoul, Robert C. ;

Janes, Sam M. ;

Lee, Siow-Ming ;

Forster, Martin ;

Ahmad, Tanya ;

Lawrence, David ;

Falzon, Mary ;

Capitanio, Arrigo ;

Harkins, Timothy T. ;

Lee, Clarence C. ;

Tom, Warren ;

Teefe, Enock ;

Chen, Shann-Ching ;

Begum, Sharmin ;

Rabinowitz, Adam ;

Phillimore, Benjamin ;

Spencer-Dene, Bradley ;

Stamp, Gordon ;

Szallasi, Zoltan ;

Matthews, Nik ;

Stewart, Aengus ;

Campbell, Peter ;

Swanton, Charles .

SCIENCE, 2014, 346 (6206) :251-256

[4] Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing [J].

Ding, Li ;

Ley, Timothy J. ;

Larson, David E. ;

Miller, Christopher A. ;

Koboldt, Daniel C. ;

Welch, John S. ;

Ritchey, Julie K. ;

Young, Margaret A. ;

Lamprecht, Tamara ;

McLellan, Michael D. ;

McMichael, Joshua F. ;

Wallis, John W. ;

Lu, Charles ;

Shen, Dong ;

Harris, Christopher C. ;

Dooling, David J. ;

Fulton, Robert S. ;

Fulton, Lucinda L. ;

Chen, Ken ;

Schmidt, Heather ;

Kalicki-Veizer, Joelle ;

Magrini, Vincent J. ;

Cook, Lisa ;

McGrath, Sean D. ;

Vickery, Tammi L. ;

Wendl, Michael C. ;

Heath, Sharon ;

Watson, Mark A. ;

Link, Daniel C. ;

Tomasson, Michael H. ;

Shannon, William D. ;

Payton, Jacqueline E. ;

Kulkarni, Shashikant ;

Westervelt, Peter ;

Walter, Matthew J. ;

Graubert, Timothy A. ;

Mardis, Elaine R. ;

Wilson, Richard K. ;

DiPersio, John F. .

NATURE, 2012, 481 (7382) :506-510

[5] Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing [J].

Gerlinger, Marco ;

Horswell, Stuart ;

Larkin, James ;

Rowan, Andrew J. ;

Salm, Max P. ;

Varela, Ignacio ;

Fisher, Rosalie ;

McGranahan, Nicholas ;

Matthews, Nicholas ;

Santos, Claudio R. ;

Martinez, Pierre ;

Phillimore, Benjamin ;

Begum, Sharmin ;

Rabinowitz, Adam ;

Spencer-Dene, Bradley ;

Gulati, Sakshi ;

Bates, Paul A. ;

Stamp, Gordon ;

Pickering, Lisa ;

Gore, Martin ;

Nicol, David L. ;

Hazell, Steven ;

Futreal, P. Andrew ;

Stewart, Aengus ;

Swanton, Charles .

NATURE GENETICS, 2014, 46 (03) :225-+

[6] Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers [J].

Govindan, Ramaswamy ;

Ding, Li ;

Griffith, Malachi ;

Subramanian, Janakiraman ;

Dees, Nathan D. ;

Kanchi, Krishna L. ;

Maher, Christopher A. ;

Fulton, Robert ;

Fulton, Lucinda ;

Wallis, John ;

Chen, Ken ;

Walker, Jason ;

McDonald, Sandra ;

Bose, Ron ;

Ornitz, David ;

Xiong, Donghai ;

You, Ming ;

Dooling, David J. ;

Watson, Mark ;

Mardis, Elaine R. ;

Wilson, Richard K. .

CELL, 2012, 150 (06) :1121-1134

[7] Comprehensive genomic characterization of squamous cell lung cancers [J].

Hammerman, Peter S. ;

Lawrence, Michael S. ;

Voet, Douglas ;

Jing, Rui ;

Cibulskis, Kristian ;

Sivachenko, Andrey ;

Stojanov, Petar ;

McKenna, Aaron ;

Lander, Eric S. ;

Gabriel, Stacey ;

Getz, Gad ;

Sougnez, Carrie ;

Imielinski, Marcin ;

Helman, Elena ;

Hernandez, Bryan ;

Pho, Nam H. ;

Meyerson, Matthew ;

Chu, Andy ;

Chun, Hye-Jung E. ;

Mungall, Andrew J. ;

Pleasance, Erin ;

Robertson, A. Gordon ;

Sipahimalani, Payal ;

Stoll, Dominik ;

Balasundaram, Miruna ;

Birol, Inanc ;

Butterfield, Yaron S. N. ;

Chuah, Eric ;

Coope, Robin J. N. ;

Corbett, Richard ;

Dhalla, Noreen ;

Guin, Ranabir ;

Hirst, Anhe Carrie ;

Hirst, Martin ;

Holt, Robert A. ;

Lee, Darlene ;

Li, Haiyan I. ;

Mayo, Michael ;

Moore, Richard A. ;

Mungall, Karen ;

Nip, Ka Ming ;

Olshen, Adam ;

Schein, Jacqueline E. ;

Slobodan, Jared R. ;

Tam, Angela ;

Thiessen, Nina ;

Varhol, Richard ;

Zeng, Thomas ;

Zhao, Yongjun ;

Jones, Steven J. M. .

NATURE, 2012, 489 (7417) :519-525

[8] Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma [J].

Johnson, Brett E. ;

Mazor, Tali ;

Hong, Chibo ;

Barnes, Michael ;

Aihara, Koki ;

McLean, Cory Y. ;

Fouse, Shaun D. ;

Yamamoto, Shogo ;

Ueda, Hiroki ;

Tatsuno, Kenji ;

Asthana, Saurabh ;

Jalbert, Llewellyn E. ;

Nelson, Sarah J. ;

Bollen, Andrew W. ;

Gustafson, W. Clay ;

Charron, Elise ;

Weiss, William A. ;

Smirnov, Ivan V. ;

Song, Jun S. ;

Olshen, Adam B. ;

Cha, Soonmee ;

Zhao, Yongjun ;

Moore, Richard A. ;

Mungall, Andrew J. ;

Jones, Steven J. M. ;

Hirst, Martin ;

Marra, Marco A. ;

Saito, Nobuhito ;

Aburatani, Hiroyuki ;

Mukasa, Akitake ;

Berger, Mitchel S. ;

Chang, Susan M. ;

Taylor, Barry S. ;

Costello, Joseph F. .

SCIENCE, 2014, 343 (6167) :189-193

[9] Evolution and Impact of Subclonal Mutations in Chronic Lymphocytic Leukemia [J].

Landau, Dan A. ;

Carter, Scott L. ;

Stojanov, Petar ;

McKenna, Aaron ;

Stevenson, Kristen ;

Lawrence, Michael S. ;

Sougnez, Carrie ;

Stewart, Chip ;

Sivachenko, Andrey ;

Wang, Lili ;

Wan, Youzhong ;

Zhang, Wandi ;

Shukla, Sachet A. ;

Vartanov, Alexander ;

Fernandes, Stacey M. ;

Saksena, Gordon ;

Cibulskis, Kristian ;

Tesar, Bethany ;

Gabriel, Stacey ;

Hacohen, Nir ;

Meyerson, Matthew ;

Lander, Eric S. ;

Neuberg, Donna ;

Brown, Jennifer R. ;

Getz, Gad ;

Wu, Catherine J. .

CELL, 2013, 152 (04) :714-726

[10] Widespread Genetic Heterogeneity in Multiple Myeloma: Implications for Targeted Therapy [J].

Lohr, Jens G. ;

Stojanov, Petar ;

Carter, Scott L. ;

Cruz-Gordillo, Peter ;

Lawrence, Michael S. ;

Auclair, Daniel ;

Sougnez, Carrie ;

Knoechel, Birgit ;

Gould, Joshua ;

Saksena, Gordon ;

Cibulskis, Kristian ;

McKenna, Aaron ;

Chapman, Michael A. ;

Straussman, Ravid ;

Levy, Joan ;

Perkins, Louise M. ;

Keats, Jonathan J. ;

Schumacher, Steven E. ;

Rosenberg, Mara ;

Getz, Gad ;

Golub, Todd R. .

CANCER CELL, 2014, 25 (01) :91-101

← 1 2 →