Is PASH Syndrome a Biofilm Disease?: A Case Series and Review of the Literature

被引:0
作者
Ead, Joey Karim [1 ]
Snyder, Robert J. [1 ]
Wise, Jaime [2 ]
Cuffy, Cherison [1 ]
Jafary, Hamed [1 ]
Fischborn, Karen [1 ]
机构
[1] Barry Univ, Sch Podiatr Med, Miami Shores, FL USA
[2] Healogics, Jacksonville, FL USA
来源
WOUNDS-A COMPENDIUM OF CLINICAL RESEARCH AND PRACTICE | 2018年 / 30卷 / 08期
关键词
biofilm; wound care; PASH syndrome; pyoderma gangrenosum; acne; hidradenitis suppurativa; chronic wounds; pathergy; HIDRADENITIS SUPPURATIVA; PYODERMA-GANGRENOSUM; CHRONIC WOUNDS; ACNE-VULGARIS; PATHOGENESIS; IDENTIFICATION; EPIDEMIOLOGY; METAANALYSIS; INFECTIONS; BACTERIA;
D O I
暂无
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Introduction. When occurring together, pyoderma gangrenosum, severe acne, and hidradenitis suppurativa have been described as PASH syndrome. Due to the chronic autoinflammatory state existing in affected patients, PASH syndrome has been attributed to the dysregulation of wound healing. Case Reports. Two cases are presented that demonstrate the paradigmatic clinical features of PASH syndrome and its potential link as an expanding spectrum of bacterial biofilm disorder. Conclusions. As reported herein, based on biofilm's clinical presentation and resistance to proper wound healing, it could serve as the common denominator and may redirect clinicians' treatment pathways in the near future.
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页码:216 / +
页数:13
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