MicroRNA-9 and breast cancer

被引：81

作者：

Li, Xiaoman ^{[1
]}

Zeng, Zhu ^{[2
]}

Wang, Jiaer ^{[2
]}

Wu, Yuanyuan ^{[1
]}

Chen, Wenxing ^{[1
]}

Zheng, Lufeng ^{[3
]}

Xi, Tao ^{[3
]}

Wang, Aiyun ^{[1
]}

Lu, Yin ^{[1
]}

机构：

[1] Nanjing Univ Chinese Med, Sch Pharm, Jiangsu Key Lab Pharmacol & Safety Evaluat Chines, Nanjing 210023, Peoples R China

[2] Nanjing Univ Chinese Med, Sch Pharm, Nanjing 210023, Peoples R China

[3] China Pharmaceut Univ, Sch Life Sci & Technol, Jiangsu Key Lab Carcinogenesis & Intervent, Nanjing 210009, Peoples R China

来源：

BIOMEDICINE & PHARMACOTHERAPY | 2020年 / 122卷

关键词：

miR-9; Breast cancer; Tumorigenesis and development; Oncogene; Tumor suppressor; EPITHELIAL-MESENCHYMAL TRANSITION; CELL-PROLIFERATION; MIR-9; EXPRESSION; DIAGNOSIS; HALLMARKS; COMPLEX; DICER; MIRNA; TRBP;

D O I：

10.1016/j.biopha.2019.109687

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Breast cancer is the most common cancer in women worldwide and seriously impairs patients' physical and mental health. Its incidence has been predicted to rise further. Mounting evidence indicates that microRNAs (miRNAs) play key roles in tumorigenesis and development. It is worth noting that miR-9 exerts critical functions in the initiation and progression of breast cancer, and the present research displays opposite roles of miR-9 in breast cancer. This article mainly reviews the roles of miR-9 in breast cancer progression.

引用

页数：5

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