Signaling in Host-Associated Microbial Communities

被引：133

作者：

Fischbach, Michael A. ^{[1
,2
]}

Segre, Julia A. ^{[3
]}

机构：

[1] Univ Calif San Francisco, Dept Bioengn & Therapeut Sci, San Francisco, CA 94143 USA

[2] Univ Calif San Francisco, Calif Inst Quantitat Biosci, San Francisco, CA 94143 USA

[3] Natl Human Genome Res Inst, Microbial Genom Sect, Translat & Funct Genom Branch, Bethesda, MD 20892 USA

来源：

CELL | 2016年 / 164卷 / 06期

关键词：

INVASIVE ESCHERICHIA-COLI; FUNGUS-GROWING ANTS; GUT MICROBIOTA; COMMENSAL; DIET; BACTERIA; SPECIFICITY; METABOLISM; PROMOTES; COLONIZATION;

D O I：

10.1016/j.cell.2016.02.037

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Human-associated microbiota form and stabilize communities based on interspecies interactions. We review how these microbe-microbe and microbe-host interactions are communicated to shape communities over a human's lifes pan,including periods of health and disease. Modeling and dissecting signaling in host-associated communities is crucial to understand their function and will open the door to therapies that prevent or correct microbial community dysfunction to promote health and treat disease.

引用

页码：1288 / 1300

页数：13

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