Magnetic nanoparticles as potential candidates for biomedical and biological applications

被引：30
|
作者：
Sehrig, Fatemeh Zeinali [1 ]
Majidi, Sima [2 ]
Nikzamir, Nasrin [1 ]
Nikzamir, Nasim [1 ]
Nikzamir, Mohammad [1 ]
Akbarzadeh, Abolfazl [1 ,2 ,3 ,4 ]
机构：
[1] Tabriz Univ Med Sci, Drug Appl Res Ctr, Tabriz 5154853431, Iran
[2] Tabriz Univ Med Sci, Biotechnol Res Ctr, Tabriz 5154853431, Iran
[3] Tabriz Univ Med Sci, Hematol & Oncol Res Ctr, Tabriz 5154853431, Iran
[4] Tabriz Univ Med Sci, Fac Adv Med Sci, Dept Med Nanotechnol, Tabriz 5154853431, Iran
来源：
ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY | 2016年 / 44卷 / 03期
关键词：
iron oxide nanoparticles; biotechnological applications; diagnostics; target; IRON-OXIDE NANOPARTICLES; SURFACE MODIFICATION; GENE-EXPRESSION; PARTICLES; FUNCTIONALIZATION; HYPERTHERMIA; DELIVERY; CELLS; SHELL; ENTEROKINASE;
D O I：
10.3109/21691401.2014.998832
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Magnetic iron oxide nanoparticles have become the main candidates for biomedical and biological applications, and the application of small iron oxide nanoparticles in in vitro diagnostics has been practiced for about half a century. Magnetic nanoparticles (MNPs), in combination with an external magnetic field and/or magnetizable grafts, allow the delivery of particles to the chosen target area, fix them at the local site while the medication is released, and act locally. In this review, we focus mostly on the potential use of MNPs for biomedical and biotechnological applications, and the improvements made in using these nanoparticles (NPs) in biological applications.
引用
收藏
页码：918 / 927
页数：10
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