Development of a Prediction Rule for Estimating Postoperative Pulmonary Complications

被引:47
作者
Jeong, Byeong-Ho [1 ]
Shin, Beomsu [1 ]
Eom, Jung Seop [2 ]
Yoo, Hongseok [1 ]
Song, Wonjun [1 ]
Han, Sangbin [3 ]
Lee, Kyung Jong [1 ]
Jeon, Kyeongman [1 ]
Um, Sang-Won [1 ]
Koh, Won-Jung [1 ]
Suh, Gee Young [1 ]
Chung, Man Pyo [1 ]
Kim, Hojoong [1 ]
Kwon, O. Jung [1 ]
Woo, Sookyoung [4 ]
Park, Hye Yun [1 ]
机构
[1] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Med,Div Pulm & Crit Care Med, Seoul, South Korea
[2] Pusan Natl Univ, Coll Med, Dept Internal Med, Pusan 609735, South Korea
[3] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Anesthesiol & Pain Med, Seoul, South Korea
[4] Samsung Biomed Res Inst, Biostat Team, Seoul, South Korea
来源
PLOS ONE | 2014年 / 9卷 / 12期
关键词
MAJOR NONCARDIAC SURGERY; COLLEGE-OF-PHYSICIANS; LAPAROSCOPIC CHOLECYSTECTOMY; NONCARDIOTHORACIC SURGERY; INCENTIVE SPIROMETRY; ABDOMINAL-SURGERY; OUTCOMES; RISK; INDEX; ASSOCIATION;
D O I
10.1371/journal.pone.0113656
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Patient-and procedure-related factors associated with postoperative pulmonary complications (PPCs) have changed over the last decade. Therefore, we sought to identify independent risk factors of PPCs and to develop a clinically applicable scoring system. We retrospectively analyzed clinical data from 2,059 patients who received preoperative evaluations from respiratory physicians between June 2011 and October 2012. A new scoring system for estimating PPCs was developed using beta coefficients of the final multiple regression models. Of the 2,059 patients studied, 140 (6.8%) had PPCs. A multiple logistic regression model revealed seven independent risk factors (with scores in parentheses): age >= 70 years (2 points), current smoker (1 point), the presence of airflow limitation (1 point), American Society of Anesthesiologists class >= 2 (1 point), serum albumin <4 g/dL (1 point), emergency surgery (2 points), and non-laparoscopic abdominal/cardiac/aortic aneurysm repair surgery (4 points). The area under the curve was 0.79 (95% CI, 0.75-0.83) with the newly developed model. The new risk stratification including laparoscopic surgery has a good discriminative ability for estimating PPCs in our study cohort. Further research is needed to validate this new prediction rule.
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页数:12
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