Role of sympathetic nervous system in protective effects of selective κ-opiate receptor agonist dynorphin A1-13 on the incidence of cardiac arrhythmia during myocardial ischemia

被引：3

作者：

Mikhailova, SD ^{[1
]}

Vasil'eva, TV ^{[1
]}

Semushkina, TM ^{[1
]}

Storozhakov, GI ^{[1
]}

机构：

[1] Russian State Med Univ, Moscow 117437, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2000年 / 129卷 / 01期

关键词：

dynorphin A(1-13); kappa-opiate receptors; myocardial ischemia; cardiac arrhythmia; stellate ganglion;

D O I：

10.1007/BF02433859

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Preliminary administration of dynorphin A(1-13) to narcotized cats with myocardial ischemia attenuated cardiac fibrillation, but increased the incidence of ventricular tachycardia. Protective effect of dynorphin A(1-13) was observed only under conditions of intact sympathetic cardiac innervation.

引用

页码：27 / 29

页数：3