Legg-Calve-Perthes disease in two generations of male family members: a case report

被引：17

作者：

Al-Omran, Ammar K. ^{[1
]}

Sadat-Ali, Mir ^{[1
]}

机构：

[1] Univ Dammam, King Fahd Hosp Univ, Coll Med, Dept Orthopaed Surg, Al Khobar, Saudi Arabia

来源：

JOURNAL OF ORTHOPAEDIC SURGERY | 2013年 / 21卷 / 02期

关键词：

femur head necrosis; Legg-Calve-Perthes disease; mutations; DYSPLASIA; MUTATIONS;

D O I：

10.1177/230949901302100230

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Legg-Calve-Perthes disease (LCPD) is a type of avascular necrosis of the femoral head occurring mainly in male children and causing early osteoarthritis. We report 2 generations of 4 male family members with LCPD-like features and mutation of the COL2A1 gene of the 12q13 chromosome. If LCPD occurs in any family member, we recommend genetic analysis and counselling as well as early radiological screening of related children.

引用

页码：258 / 261

页数：4

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