Airway clearance modalities in neuromuscular disease

被引:32
作者
Finder, Jonathan D. [1 ,2 ]
机构
[1] Univ Pittsburgh, Sch Med, Pittsburgh, PA 15260 USA
[2] Childrens Hosp Pittsburgh, Pittsburgh, PA 15213 USA
关键词
airway clearance; mechanical insufflation-exsufflation; cough; neuromuscular; weakness; MECHANICAL INSUFFLATION-EXSUFFLATION; INTRAPULMONARY PERCUSSIVE VENTILATION; DUCHENNE MUSCULAR-DYSTROPHY; COUGH; CHILDREN; FLOWS; PROLONGATION; MANAGEMENT; CAPACITY; WEAKNESS;
D O I
10.1016/j.prrv.2009.10.007
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Airway clearance consists of two linked processes: mucociliary clearance and cough clearance. Patients with neuromuscular weakness are at risk for impaired cough clearance and therefore the development of pneumonia and atelectasis. Aiding airway clearance in the patient with neuromuscular weakness is critical to the maintenance of health and the prevention of significant respiratory morbidity. This can be achieved using both manual and mechanical techniques. This review will discuss the physiology of cough and the mechanics of aiding cough clearance in the patient with neuromuscular weakness. In addition, technologies and techniques used to improve mucociliary clearance will also be discussed. Newer technologies such as mechanical insufflation-exsufflation have gained widespread acceptance in the management of airway clearance in the patient with neuromuscular weakness. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码:31 / 34
页数:4
相关论文
共 27 条
[1]   MECHANICAL INSUFFLATION-EXSUFFLATION - COMPARISON OF PEAK EXPIRATORY FLOWS WITH MANUALLY ASSISTED AND UNASSISTED COUGHING TECHNIQUES [J].
BACH, JR .
CHEST, 1993, 104 (05) :1553-1562
[2]   Amyotrophic lateral sclerosis - Prolongation of life by noninvasive respiratory aids [J].
Bach, JR .
CHEST, 2002, 122 (01) :92-98
[3]   Spinal muscular atrophy type 1: Management and outcomes [J].
Bach, JR ;
Baird, JS ;
Plosky, D ;
Navado, J ;
Weaver, B .
PEDIATRIC PULMONOLOGY, 2002, 34 (01) :16-22
[4]   UPDATE AND PERSPECTIVE ON NONINVASIVE RESPIRATORY MUSCLE AIDS .2. THE EXPIRATORY AIDS [J].
BACH, JR .
CHEST, 1994, 105 (05) :1538-1544
[5]  
BARACH A. L., 1952, JOUR APPL PHYSIOL, V5, P85
[6]   PHYSICAL METHODS SIMULATING MECHANISMS OF THE HUMAN COUGH - ELIMINATION OF RADIOPAQUE MATERIAL FROM THE BRONCHI OF DOGS [J].
BICKERMAN, HA ;
BECK, GJ ;
GORDON, C ;
BARACH, AL .
JOURNAL OF APPLIED PHYSIOLOGY, 1952, 5 (02) :92-98
[7]  
Birnkrant DJ, 1996, PEDIATR PULM, V21, P246
[8]   Cough augmentation with mechanical insufflation/exsufflation in patients with neuromuscular weakness [J].
Chatwin, M ;
Ross, E ;
Hart, N ;
Nickol, AH ;
Polkey, MI ;
Simonds, AK .
EUROPEAN RESPIRATORY JOURNAL, 2003, 21 (03) :502-508
[9]   Relationship between supramaximal flow during cough and mortality in motor neurone disease [J].
Chaudri, MB ;
Liu, C ;
Hubbard, R ;
Jefferson, D ;
Kinnear, WJ .
EUROPEAN RESPIRATORY JOURNAL, 2002, 19 (03) :434-438
[10]  
Deakins Kathleen, 2002, Respir Care, V47, P1162