Graphene Quantum Dots and Their Applications in Bioimaging, Biosensing, and Therapy

被引：258

作者：

Chung, Seokhwan ^{[1
]}

Revia, Richard A. ^{[1
]}

Zhang, Miqin ^{[1
]}

机构：

[1] Univ Washington, Dept Mat Sci & Engn, Seattle, WA 98195 USA

来源：

ADVANCED MATERIALS | 2021年 / 33卷 / 22期

基金：

美国国家卫生研究院;

关键词：

bioimaging; drug delivery; graphene; nanomedicine; quantum dots; DOPED CARBON DOTS; ONE-POT SYNTHESIS; DEPENDENT ELECTROCATALYTIC ACTIVITY; ONE-STEP SYNTHESIS; RAPID SYNTHESIS; ELECTROCHEMICAL PREPARATION; ELECTRICAL-PROPERTIES; HYDROTHERMAL ROUTE; FACILE PREPARATION; DEEP-ULTRAVIOLET;

D O I：

10.1002/adma.201904362

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Graphene quantum dots (GQDs) are carbon-based, nanoscale particles that exhibit excellent chemical, physical, and biological properties that allow them to excel in a wide range of applications in nanomedicine. The unique electronic structure of GQDs confers functional attributes onto these nanomaterials such as strong and tunable photoluminescence for use in fluorescence bioimaging and biosensing, a high loading capacity of aromatic compounds for small-molecule drug delivery, and the ability to absorb incident radiation for use in the cancer-killing techniques of photothermal and photodynamic therapy. Recent advances in the development of GQDs as novel, multifunctional biomaterials are presented with a focus on their physicochemical, electronic, magnetic, and biological properties, along with a discussion of technical progress in the synthesis of GQDs. Progress toward the application of GQDs in bioimaging, biosensing, and therapy is reviewed, along with a discussion of the current limitations and future directions of this exciting material.

引用

页数：26

共 140 条

[1] Tuning electronic properties in graphene quantum dots by chemical functionalization: Density functional theory calculations [J].