Treatment of hepatitis C before and after liver transplantation

被引：1

作者：

Liovet, Laura-Patricia ^{[1
]}

Rodriguez-Tajesy, Sergio ^{[1
]}

Londono, Maria-Carlota ^{[1
]}

机构：

[1] Hosp Clin Barcelona, CIBEREHD, IDIBAPS, Serv Hepatol, Barcelona, Spain

来源：

GASTROENTEROLOGIA Y HEPATOLOGIA | 2016年 / 39卷 / 05期

关键词：

Liver transplantation; Hepatitis C; Direct antiviral agents; HCV INFECTION; GENOTYPE; DECOMPENSATED CIRRHOSIS; VIROLOGICAL RESPONSE; FIBROSIS PROGRESSION; SOFOSBUVIR; RIBAVIRIN; RECURRENCE; DACLATASVIR; MULTICENTER;

D O I：

10.1016/j.gastrohep.2015.09.002

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Hepatitis C recurrence after liver transplantation is universal and increases morbidity and mortality in these patients. The development of new direct antiviral agents against the hepatitis C virus is a major treatment advance. Pre-transplant treatment avoids graft infection and sometimes improves liver function, allowing the patient to be withdrawn from the transplant waiting list. Delaying treatment until the postpostransplant period may be advisable in patients with advanced cirrhosis. Generally, antiviral therapy after liver transplantation is provided in patients with histological evidence of the disease. In these patients, treatment is more effective in the initial stages of the disease. The choice of antiviral therapy in these patients is based on the degree of liver function, the presence of renal failure, and potential drug-drug interactions. (C) 2015 Elsevier Espana, S.L.U. and AEEH y AEG. All rights reserved.

引用

页码：344 / 351

页数：8

共 43 条

[1]

Afdhal N, 2015, ABSTRACT J HEPATOL, V62, P5269

[2] Ledipasvir and Sofosbuvir for Untreated HCV Genotype 1 Infection [J].

Afdhal, Nezam ;

Zeuzem, Stefan ;

Kwo, Paul ;

Chojkier, Mario ;

Gitlin, Norman ;

Puoti, Massimo ;

Romero-Gomez, Manuel ;

Zarski, Jean-Pierre ;

Agarwal, Kosh ;

Buggisch, Peter ;

Foster, Graham R. ;

Braeu, Norbert ;

Buti, Maria ;

Jacobson, Ira M. ;

Subramanian, G. Mani ;

Ding, Xiao ;

Mo, Hongmei ;

Yang, Jenny C. ;

Pang, Phillip S. ;

Symonds, William T. ;

McHutchison, John G. ;

Muir, Andrew J. ;

Mangia, Alessandra ;

Marcellin, Patrick .

NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (20) :1889-1898

[3] Ledipasvir and Sofosbuvir for Previously Treated HCV Genotype 1 Infection [J].

Afdhal, Nezam ;

Reddy, K. Rajender ;

Nelson, David R. ;

Lawitz, Eric ;

Gordon, Stuart C. ;

Schiff, Eugene ;

Nahass, Ronald ;

Ghalib, Reem ;

Gitlin, Norman ;

Herring, Robert ;

Lalezari, Jacob ;

Younes, Ziad H. ;

Pockros, Paul J. ;

Di Bisceglie, Adrian M. ;

Arora, Sanjeev ;

Subramanian, G. Mani ;

Zhu, Yanni ;

Dvory-Sobol, Hadas ;

Yang, Jenny C. ;

Pang, Phillip S. ;

Symonds, William T. ;

McHutchison, John G. ;

Muir, Andrew J. ;

Sulkowski, Mark ;

Kwo, Paul .

NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (16) :1483-1493

[4] Liver transplantation for HCV cirrhosis:: Improved survival in recent years and increased severity of recurrent disease in female recipients:: Results of a long term retrospective study [J].

Belli, Luca S. ;

Burroughs, Andrew K. ;

Burra, Patrizia ;

Alberti, Alberto B. ;

Samonakis, Dimitrios ;

Camma, Calogero ;

De Carlis, Luciano ;

Minola, Ernesto ;

Quaglia, Alberto ;

Zavaglia, Claudio ;

Vangeli, Morcello ;

Patch, David ;

Dhillon, Amar ;

Cillo, Umberto ;

Guido, Maria ;

Fagiuoli, Stefano ;

Giacomoni, Alessandro ;

Slim, Omar A. ;

Airoldi, Aldo ;

Boninsegna, Sara ;

Davidson, Brian R. ;

Rolles, Keith ;

Pinzello, Giovambattista .

LIVER TRANSPLANTATION, 2007, 13 (05) :733-740

[5] Natural history of clinically compensated hepatitis C virus-related graft cirrhosis after liver transplantation [J].

Berenguer, M ;

Prieto, M ;

Rayón, JM ;

Mora, J ;

Pastor, M ;

Ortiz, V ;

Carrasco, D ;

San Juan, F ;

Burgueño, MDJ ;

Mir, J ;

Berenguer, J .

HEPATOLOGY, 2000, 32 (04) :852-858

[6] HCV-related fibrosis progression following liver transplantation:: increase in recent years [J].

Berenguer, M ;

Ferrell, L ;

Watson, J ;

Prieto, M ;

Kim, M ;

Rayón, M ;

Córdoba, J ;

Herola, A ;

Ascher, N ;

Mir, J ;

Berenguer, J ;

Wright, TL .

JOURNAL OF HEPATOLOGY, 2000, 32 (04) :673-684

[7] A US multicenter study of hepatitis C treatment of liver transplant recipients with protease-inhibitor triple therapy [J].

Burton, James R., Jr. ;

O'Leary, Jacqueline G. ;

Verna, Elizabeth C. ;

Saxena, Varun ;

Dodge, Jennifer L. ;

Stravitz, Richard T. ;

Levitsky, Joshua ;

Trotter, James F. ;

Everson, Gregory T. ;

Brown, Robert S., Jr. ;

Terrault, Norah A. .

JOURNAL OF HEPATOLOGY, 2014, 61 (03) :508-514

[8] Pre-emptive treatment of recurrent hepatitis C infection [J].

Charlton, M .

LIVER TRANSPLANTATION, 2002, 8 (10) :S50-S54

[9] Sofosbuvir and Ribavirin for Treatment of Compensated Recurrent Hepatitis C Virus Infection After Liver Transplantation [J].

Charlton, Michael ;

Gane, Edward ;

Manns, Michael P. ;

Brown, Robert S., Jr. ;

Curry, Michael P. ;

Kwo, Paul Y. ;

Fontana, Robert J. ;

Gilroy, Richard ;

Teperman, Lewis ;

Muir, Andrew J. ;

McHutchison, John G. ;

Symonds, William T. ;

Brainard, Diana ;

Kirby, Brian ;

Dvory-Sobol, Hadas ;

Denning, Jill ;

Arterburn, Sarah ;

Samuel, Didier ;

Forns, Xavier ;

Terrault, Norah A. .

GASTROENTEROLOGY, 2015, 148 (01) :108-117

[10] THE ASSOCIATION OF SOFOSBUVIR AND DACLATASVIR FOR TREATING SEVERE RECURRENCE OF HCV INFECTION AFTER LIVER TRANSPLANTATION: RESULTS FROM A LARGE FRENCH PROSPECTIVE MULTICENTRIC ANRS CO23 CUPILT COHORT [J].

Coilly, A. ;

Fougerou, C. ;

De Ledinghen, V. ;

Houssel-Debry, P. ;

Duvoux, C. ;

Di Martino, V. ;

Radenne, S. ;

Kamar, N. ;

D'Alteroche, L. ;

Leroy, V. ;

Canva, V. ;

Lebray, P. ;

Moreno, C. ;

Dumortier, J. ;

Silvain, C. ;

Besch, C. ;

Perre, P. ;

Botta-Fridlund, D. ;

Anty, R. ;

Rohel, A. ;

Renault, A. ;

Danjou, H. ;

Duclos-Vallee, J. -C. ;

Pageaux, G. -P. .

JOURNAL OF HEPATOLOGY, 2015, 62 :S236-S237

← 1 2 3 4 5 →