Rhodamines NN: A Novel Class of Caged Fluorescent Dyes

被引：150
|
作者：
Belov, Vladimir N. [1 ]
Wurm, Christian A. [1 ]
Boyarskiy, Vadim P. [1 ]
Jakobs, Stefan [1 ]
Hell, Stefan W. [1 ]
机构：
[1] Max Planck Inst Biophys Chem, Dept NanoBiophoton, D-37077 Gottingen, Germany
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 20期
关键词：
caged compounds; diazo compounds; fluorescence; imaging agents; rhodamines; PHOTOLABILE PROTECTING GROUPS; CROSS-SECTIONS; FLUOROPHORES; NANOSCOPY; PROTEINS; PHOTOACTIVATION; PHOTOCHROMISM; MICROSCOPY; RELEASE;
D O I：
10.1002/anie.201000150
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Figure Presented). A bright future: The reaction of diazomethane with acid chlorides obtained from N,N,N′,N′-tetraalkylrhodamines affords 2-diazo-2,3-dihydro-1Hindenespiro[1,9′]-9H-xanthen-3-ones-a novel class of caged rhodamines. These dyes allow new imaging procedures based on the step-wise activation and detection of several fluorescent markers (see picture). © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码：3520 / 3523
页数：4
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