Rhodamines NN: A Novel Class of Caged Fluorescent Dyes

被引：154

作者：

Belov, Vladimir N. ^{[1
]}

Wurm, Christian A. ^{[1
]}

Boyarskiy, Vadim P. ^{[1
]}

Jakobs, Stefan ^{[1
]}

Hell, Stefan W. ^{[1
]}

机构：

[1] Max Planck Inst Biophys Chem, Dept NanoBiophoton, D-37077 Gottingen, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 20期

关键词：

caged compounds; diazo compounds; fluorescence; imaging agents; rhodamines; PHOTOLABILE PROTECTING GROUPS; CROSS-SECTIONS; FLUOROPHORES; NANOSCOPY; PROTEINS; PHOTOACTIVATION; PHOTOCHROMISM; MICROSCOPY; RELEASE;

D O I：

10.1002/anie.201000150

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented). A bright future: The reaction of diazomethane with acid chlorides obtained from N,N,N′,N′-tetraalkylrhodamines affords 2-diazo-2,3-dihydro-1Hindenespiro[1,9′]-9H-xanthen-3-ones-a novel class of caged rhodamines. These dyes allow new imaging procedures based on the step-wise activation and detection of several fluorescent markers (see picture). © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：3520 / 3523

页数：4

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