Prostate and lymph node proton magnetic resonance (MR) spectroscopic Imaging with external array coils at 3 T to detect recurrent prostate cancer after radiation therapy

被引：22
作者：
Heijmink, Stijn W. T. P. J.
Scheenen, Tom W. J.
Futterer, Jurgen J.
Klomp, Dennis W. J.
Heesakkers, Roel A. M.
Hulsbergen-van de Kaa, Christina A.
van Lin, Emile N. J. Th.
Heerschap, Arend
Barentsz, Jelle O.
机构：
[1] Radboud Univ Nijmegen, Med Ctr, Dept Radiol, NL-6500 HB Nijmegen, Netherlands
[2] Radboud Univ Nijmegen, Med Ctr, Dept Pathol, NL-6500 HB Nijmegen, Netherlands
[3] Radboud Univ Nijmegen, Med Ctr, Dept Radiat Oncol, NL-6500 HB Nijmegen, Netherlands
来源：
INVESTIGATIVE RADIOLOGY | 2007年 / 42卷 / 06期
关键词：
prostate; neoplasms; magnetic resonance (MR); spectroscopy; lymphatic system; choline;
D O I：
10.1097/01.rli.0000262759.46364.50
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
In a patient suspected of having recurrent prostate cancer after radiation therapy, we demonstrate the feasibility of noninvasive proton magnetic resonance spectroscopic (H-1-MRS) imaging of the prostate and a lymph node at 3 T using a matrix of external surface coils. Written informed consent was obtained from the patient. With H-1-MRS imaging, high choline with low citrate signal was observed in the prostate, and in the lymph node a signal of choline-containing compounds was identified. The tissue level of the compounds in the enlarged lymph node was estimated to be 8.1 mmol/kg water. Subsequent histopathological analysis of systematic transrectal ultrasound-guided prostate biopsy and computed tomography-guided biopsy of the lymph node confirmed the presence of prostate cancer in both.
引用
收藏
页码：420 / 427
页数：8
相关论文
共 46 条
[31]  
ORDIDGE RJ, 1987, ANN NY ACAD SCI, V508, P376
[32]   Contemporary update of prostate cancer staging nomograms (Partin Tables) for the new millennium [J].
Partin, AW ;
Mangold, LA ;
Lamm, DM ;
Walsh, PC ;
Epstein, JI ;
Pearson, JD .
UROLOGY, 2001, 58 (06) :843-848
[33]   Time to metabolic atrophy after permanent prostate seed implantation based on magnetic resonance spectroscopic imaging [J].
Pickett, B ;
Ten Haken, RK ;
Kurhanewicz, J ;
Qayyum, A ;
Shinohara, K ;
Fein, B ;
Roach, M .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2004, 59 (03) :665-673
[34]   Three-dimensional conformal external beam radiotherapy compared with permanent prostate implantation in low-risk prostate cancer based on endorectal magnetic resonance spectroscopy imaging and prostate-specific antigen level [J].
Pickett, Barby ;
Kurhanewicz, John ;
Pouliot, Jean ;
Weinberg, Vivian ;
Shinohara, Katsuto ;
Coakley, Fergus ;
Roach, Mack, III .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2006, 65 (01) :65-72
[35]   Human breast lesions: Characterization with proton MR spectroscopy [J].
Roebuck, JR ;
Cecil, KM ;
Schnall, MD ;
Lenkinski, RE .
RADIOLOGY, 1998, 209 (01) :269-275
[36]  
Ross PL, 2001, J UROLOGY, V165, P1562, DOI 10.1016/S0022-5347(05)66349-5
[37]   Optimal timing for in vivo 1H-MR spectroscopic imaging of the human prostate at 3T [J].
Scheenen, TWJ ;
Gambarota, G ;
Weiland, E ;
Klomp, DWJ ;
Fütterer, JJ ;
Barentsz, JO ;
Heerschap, A .
MAGNETIC RESONANCE IN MEDICINE, 2005, 53 (06) :1268-1274
[38]   Fast acquisition-weighted three-dimensional proton MR spectroscopic imaging of the human prostate [J].
Scheenen, TWJ ;
Klomp, DWJ ;
Röll, SA ;
Fütterer, JJ ;
Barentsz, JO ;
Heerschap, A .
MAGNETIC RESONANCE IN MEDICINE, 2004, 52 (01) :80-88
[39]   MR imaging of the prostate at 3 Tesla: Comparison of an external phased-array coil to imaging with an endorectal coil at 1.5 Tesla [J].
Sosna, J ;
Pedrosa, I ;
Dewolf, WC ;
Mahallati, H ;
Lenkinski, RE ;
Rofsky, NM .
ACADEMIC RADIOLOGY, 2004, 11 (08) :857-862
[40]   Preoperative grading of gliomas by using metabolite quantification with high-spatial-resolution proton MR spectroscopic imaging [J].
Stadlbauer, A ;
Gruber, S ;
Nimsky, C ;
Fahlbusch, R ;
Hammen, T ;
Buslei, R ;
Tomandl, B ;
Moser, E ;
Ganslandt, O .
RADIOLOGY, 2006, 238 (03) :958-969
12345