Prostate and lymph node proton magnetic resonance (MR) spectroscopic Imaging with external array coils at 3 T to detect recurrent prostate cancer after radiation therapy

被引：22
作者：
Heijmink, Stijn W. T. P. J.
Scheenen, Tom W. J.
Futterer, Jurgen J.
Klomp, Dennis W. J.
Heesakkers, Roel A. M.
Hulsbergen-van de Kaa, Christina A.
van Lin, Emile N. J. Th.
Heerschap, Arend
Barentsz, Jelle O.
机构：
[1] Radboud Univ Nijmegen, Med Ctr, Dept Radiol, NL-6500 HB Nijmegen, Netherlands
[2] Radboud Univ Nijmegen, Med Ctr, Dept Pathol, NL-6500 HB Nijmegen, Netherlands
[3] Radboud Univ Nijmegen, Med Ctr, Dept Radiat Oncol, NL-6500 HB Nijmegen, Netherlands
来源：
INVESTIGATIVE RADIOLOGY | 2007年 / 42卷 / 06期
关键词：
prostate; neoplasms; magnetic resonance (MR); spectroscopy; lymphatic system; choline;
D O I：
10.1097/01.rli.0000262759.46364.50
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
In a patient suspected of having recurrent prostate cancer after radiation therapy, we demonstrate the feasibility of noninvasive proton magnetic resonance spectroscopic (H-1-MRS) imaging of the prostate and a lymph node at 3 T using a matrix of external surface coils. Written informed consent was obtained from the patient. With H-1-MRS imaging, high choline with low citrate signal was observed in the prostate, and in the lymph node a signal of choline-containing compounds was identified. The tissue level of the compounds in the enlarged lymph node was estimated to be 8.1 mmol/kg water. Subsequent histopathological analysis of systematic transrectal ultrasound-guided prostate biopsy and computed tomography-guided biopsy of the lymph node confirmed the presence of prostate cancer in both.
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收藏
页码：420 / 427
页数：8
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