Spectrum of cystic neoplasms of the pancreas and their surgical management

Background: Owing to increased awareness and the widespread use of abdominal ultrasonography and computed tomography, an increasing number of cystic neoplasms are being identified. Cystic neoplasms of the pancreas are divided into the following 4 main groups: serous cystic neoplasms, mucinous cystic neoplasms, solid pseudopapillary neoplasms, and intraductal pancreatic mucinous neoplasms. Objective: To review our experience with cystic neoplasms of the pancreas at our institution from January 1092 through September 2002. Methods: Medical records were reviewed for age, sex, clinical signs and symptoms, diagnosis, surgical treatment, morbidity, mortality, and histologic features. Results: Seventy-three patients (49 women and 24 men) underwent surgical resection of a cystic neoplasm of the pancreas, from January 1992 through September 2002. The most common presenting symptom was abdominal pain. Other symptoms included nausea, emesis, weight loss, jaundice, and pancreatitis. Most patients (73%) had no complications. The most common complication (10%) was pancreatic fistula. There were 3 deaths. Conclusions: Cystic neoplasms of the pancreas are an increasing entity. Long-term survival of patients with these tumors is generally better than that of patients with adenocarcinoma of the pancreas and mandates Aggressive resectional therapy in most patients. Resection of these tumors can be done with resultant low morbidity and mortality rates.