A NEW SYNTHESIS OF NOVEL TRICYCLIC 2(5H)-FURANONE HETEROCYCLES FROM 3,4,5-TRICHLORO-2(5H)-FURANONE

被引：5
|
作者：
Ren, Jian [1 ]
Ma, Dan-Dan [1 ]
Sha, Yu [1 ]
Li, Feng [1 ]
Cheng, Mao-Sheng [1 ]
机构：
[1] Shenyang Pharmaceut Univ, Sch Pharmaceut Engn, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Peoples R China
来源：
HETEROCYCLES | 2010年 / 81卷 / 06期
关键词：
2(5H)-Furanone Heterocycle; 2-Chloromethylquinoxaline; Mucochloric Acid; 3,4,5-Trichloro-2(5H)-furanone; Bifunctional O-Nucleophile;
D O I：
10.3987/COM-10-11923
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel class of five-six-six tricyclic 2(5H)-furanone heterocycles was synthesized from 3,4,5-trichloro-2(5H)-furanone and bifunctional o-nucleophiles in a single step. In addition, 2-(chloromethyl)quinoxaline was obtained through this method, and the distinctive formation mechanism of this compound is discussed.
引用
收藏
页码：1427 / 1434
页数：8
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