Caenorhabditis elegans as a Model System for Duchenne Muscular Dystrophy

被引：5

作者：

Ellwood, Rebecca A. ^{[1
,2
]}

Piasecki, Mathew ^{[1
,2
]}

Szewczyk, Nathaniel J. ^{[1
,2
,3
,4
]}

机构：

[1] Univ Nottingham, Med Res Council MRC Versus Arthrit, Ctr Musculoskeletal Ageing Res, Royal Derby Hosp, Derby DE22 3DT, England

[2] Nottingham Biomed Res Ctr, Natl Inst Hlth Res, Derby DE22 3DT, England

[3] Ohio Univ, Ohio Musculoskeletal & Neurol Inst, Athens, OH 45701 USA

[4] Ohio Univ, Dept Biomed Sci, Heritage Coll Osteopath Med, Athens, OH 45701 USA

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2021年 / 22卷 / 09期

基金：

英国生物技术与生命科学研究理事会;

关键词：

DMD; C; elegans; dystrophin; muscle; CARBONIC-ANHYDRASE-III; MUSCLE DEGENERATION; MDX MOUSE; ALPHA-CATULIN; BK CHANNEL; DYSTROBREVIN; GENE; INHIBITION; EXPRESSION; INTEGRITY;

D O I：

10.3390/ijms22094891

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The nematode worm Caenorhabditis elegans has been used extensively to enhance our understanding of the human neuromuscular disorder Duchenne Muscular Dystrophy (DMD). With new arising clinically relevant models, technologies and treatments, there is a need to reconcile the literature and collate the key findings associated with this model.

引用

页数：19

共 50 条

[1] MUSCLE CELLS OF Caenorhabditis elegans AS AN EXPERIMENTAL MODEL FOR NEW METHODS OF THERAPY OF DUCHENNE MUSCULAR DYSTROPHY
Czyzewska-Majchrzak, Lucja
POSTEPY BIOLOGII KOMORKI, 2010, 37 (03) : 613 - 629
[2] Mitochondrial hydrogen sulfide supplementation improves health in the C. elegans Duchenne muscular dystrophy model
Ellwood, Rebecca A.
Hewitt, Jennifer E.
Torregrossa, Roberta
Philp, Ashleigh M.
Hardee, Justin P.
Hughes, Samantha
van de Klashorst, David
Gharahdaghi, Nima
Anupom, Taslim
Slade, Luke
Deane, Colleen S.
Cooke, Michael
Etheridge, Timothy
Piasecki, Mathew
Antebi, Adam
Lynch, Gordon S.
Philp, Andrew
Vanapalli, Siva A.
Whiteman, Matthew
Szewczyk, Nathaniel J.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 118 (09)
[3] CRISPR Correction of Duchenne Muscular Dystrophy
Min, Yi-Li
Bassel-Duby, Rhonda
Olson, Eric N.
ANNUAL REVIEW OF MEDICINE, VOL 70, 2019, 70 : 239 - 255
[4] Exon-skipping therapy for Duchenne muscular dystrophy
Nakamura, Akinori
Takeda, Shin'ichi
NEUROPATHOLOGY, 2009, 29 (04) : 494 - 501
[5] Physical exertion exacerbates decline in the musculature of an animal model of Duchenne muscular dystrophy
Hughes, K. J.
Rodriguez, A.
Flatt, K. M.
Ray, S.
Schuler, A.
Rodemoyer, B.
Veerappan, V.
Cuciarone, K.
Kullman, A.
Lim, C.
Gutta, N.
Vemuri, S.
Andriulis, V.
Niswonger, D.
Barickman, L.
Stein, W.
Singhvi, A.
Schroeder, N. E.
Vidal-Gadea, A. G.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 116 (09) : 3508 - 3517
[6] Muscle strength deficiency and mitochondrial dysfunction in a muscular dystrophy model of Caenorhabditis elegans and its functional response to drugs
Hewitt, Jennifer E.
Pollard, Amelia K.
Lesanpezeshki, Leila
Deane, Colleen S.
Gaffney, Christopher J.
Etheridge, Timothy
Szewczyk, Nathaniel J.
Vanapalli, Siva A.
DISEASE MODELS & MECHANISMS, 2018, 11 (12)
[7] Duchenne muscular dystrophy
von Moers, A.
NERVENHEILKUNDE, 2011, 30 (10) : 805 - +
[8] THE ROLE OF MITOCHONDRIA IN DUCHENNE MUSCULAR DYSTROPHY
Budzinska, M.
Zimna, A.
Kurpisz, M.
JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 2021, 72 (02): : 1 - 10
[9] A novel rabbit model of Duchenne muscular dystrophy generated by CRISPR/Cas9
Sui, Tingting
Lau, Yeh Siang
Liu, Di
Liu, Tingjun
Xu, Li
Gao, Yandi
Lai, Liangxue
Li, Zhanjun
Han, Renzhi
DISEASE MODELS & MECHANISMS, 2018, 11 (06)
[10] Mechanisms and Consequences of Cerebellar Purkinje Cell Disinhibition in a Mouse Model of Duchenne Muscular Dystrophy
Wu, Wan-Chen
Bradley, Samual P.
Christie, Jason M.
Pugh, Jason R.
JOURNAL OF NEUROSCIENCE, 2022, 42 (10) : 2103 - 2115

← 1 2 3 4 5 →