New Methodologies for the Synthesis of 3-Acylpyridone Metabolites

被引：11

作者：

Jones, Raymond C. F. ^{[1
]}

Choudhury, Abdul K. ^{[1
]}

Iley, James N. ^{[2
]}

Loizou, Georgia ^{[2
]}

Lumley, Christopher ^{[1
]}

McKee, Vickie ^{[1
]}

机构：

[1] Univ Loughborough, Dept Chem, Loughborough LE11 3TU, Leics, England

[2] Open Univ, Dept Chem, Milton Keynes MK7 6AA, Bucks, England

来源：

SYNLETT | 2010年 / 04期

关键词：

heterocycles; cycloaddition; metalation; aldol reaction; pyridone; 1,3-DIPOLAR CYCLOADDITION ROUTE; BEAUVERIA-BASSIANA; ENTOMOPATHOGENIC FUNGUS; PAECILOMYCES-MILITARIS; HETEROCYCLIC TRIONES; TENELLIN; ACIDS; PYRIDOMACROLIDIN; PYRIDOVERICIN; BIOSYNTHESIS;

D O I：

10.1055/s-0029-1219341

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A core isoxazolo[4,3-c]pyridin-4-one scaffold is prepared and elaborated at C-3(Me) and C-7 as a masked building block for 3-acylpyridin-2-ones related to the acylpyridone natural products.

引用

页码：654 / 658

页数：5

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