Sodium dithionite-initiated coupling of 1-bromo-1-chloro-2,2,2-trifluoroethane with pyrroles: A new, convenient and economical synthesis of 5-(trifluoromethyl)dipyrromethanes

被引：0

作者：

Dmowski, W ^{[1
]}

Piasecka-Maciejewska, K ^{[1
]}

Urbanczyk-Lipkowska, Z ^{[1
]}

机构：

[1] Polish Acad Sci, Inst Organ Chem, PL-01224 Warsaw, Poland

来源：

SYNTHESIS-STUTTGART | 2003年 / 06期

关键词：

5-(trifluoromethyl)dipyrromethanes; pyrroles; 1-bromo-1-chloro-2,2,2-trifluoroethane; sodium dithionite;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sodium dithionite-initiated reactions of pyrrole and 1-methylpyrrole with 1-bromo-1-chloro-2,2,2-ethane in an acetonitrile-water mixture provide the respective 5-(trifluoromethyl)dipyrromethanes I and 3 as main products in 40-58% isolated yields and of high purity. Small amounts of tripyrranes 2 and 4 are also formed and could be isolated from the reaction mixtures.

引用

页码：841 / 844

页数：4

共 13 条

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