MPL mutation effect on JAK2 46/1 haplotype frequency in JAK2V617F-negative myeloproliferative neoplasms

被引:21
作者
Patnaik, M. M. [1 ]
Lasho, T. L. [1 ]
Finke, C. M. [1 ]
Gangat, N. [1 ]
Caramazza, D. [2 ]
Siragusa, S. [2 ]
Hanson, C. A. [3 ]
Pardanani, A. [1 ]
Tefferi, A. [1 ]
机构
[1] Mayo Clin, Dept Med, Div Hematol, Rochester, MN 55905 USA
[2] Policlin Univ Palermo, Cattedra & UO Ematol, Palermo, Italy
[3] Mayo Clin, Dept Lab Med, Div Hematopathol, Rochester, MN USA
关键词
CONFERS SUSCEPTIBILITY; ESSENTIAL THROMBOCYTHEMIA; PRIMARY MYELOFIBROSIS; POLYCYTHEMIA-VERA; REGARDLESS; DISORDERS; SURVIVAL; INFERIOR;
D O I
10.1038/leu.2010.1
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:859 / 860
页数:3
相关论文
共 12 条
[1]   Mutations of ASXL1 gene in myeloproliferative neoplasms [J].
Carbuccia, N. ;
Murati, A. ;
Trouplin, V. ;
Brecqueville, M. ;
Adelaide, J. ;
Rey, J. ;
Vainchenker, W. ;
Bernard, O. A. ;
Chaffanet, M. ;
Vey, N. ;
Birnbaum, D. ;
Mozziconacci, M. J. .
LEUKEMIA, 2009, 23 (11) :2183-2186
[2]   JAK2 haplotype is a major risk factor for the development of myeloproliferative neoplasms [J].
Jones, Amy V. ;
Chase, Andrew ;
Silver, Richard T. ;
Oscier, David ;
Zoi, Katerina ;
Wang, Y. Lynn ;
Cario, Holger ;
Pahl, Heike L. ;
Collins, Andrew ;
Reiter, Andreas ;
Grand, Francis ;
Cross, Nicholas C. P. .
NATURE GENETICS, 2009, 41 (04) :446-449
[3]   A germline JAK2 SNP is associated with predisposition to the development of JAK2V617F-positive myeloproliferative neoplasms [J].
Kilpivaara, Outi ;
Mukherjee, Semanti ;
Schram, Alison M. ;
Wadleigh, Martha ;
Mullally, Ann ;
Ebert, Benjamin L. ;
Bass, Adam ;
Marubayashi, Sachie ;
Heguy, Adriana ;
Garcia-Manero, Guillermo ;
Kantarjian, Hagop ;
Offit, Kenneth ;
Stone, Richard M. ;
Gilliland, D. Gary ;
Klein, Robert J. ;
Levine, Ross L. .
NATURE GENETICS, 2009, 41 (04) :455-459
[4]   The 'GGCC' haplotype of JAK2 confers susceptibility to JAK2 exon 12 mutation-positive polycythemia vera [J].
Olcaydu, D. ;
Skoda, R. C. ;
Looser, R. ;
Li, S. ;
Cazzola, M. ;
Pietra, D. ;
Passamonti, F. ;
Lippert, E. ;
Carillo, S. ;
Girodon, F. ;
Vannucchi, A. ;
Reading, N. S. ;
Prchal, J. T. ;
Ay, C. ;
Pabinger, I. ;
Gisslinger, H. ;
Kralovics, R. .
LEUKEMIA, 2009, 23 (10) :1924-1926
[5]   A common JAK2 haplotype confers susceptibility to myeloproliferative neoplasms [J].
Olcaydu, Damla ;
Harutyunyan, Ashot ;
Jaeger, Roland ;
Berg, Tiina ;
Gisslinger, Bettina ;
Pabinger, Ingrid ;
Gisslinger, Heinz ;
Kralovics, Robert .
NATURE GENETICS, 2009, 41 (04) :450-454
[6]   The JAK2 46/1 haplotype confers susceptibility to essential thrombocythemia regardless of JAK2V617F mutational status-clinical correlates in a study of 226 consecutive patients [J].
Pardanani, A. ;
Lasho, T. L. ;
Finke, C. M. ;
Gangat, N. ;
Wolanskyj, A. P. ;
Hanson, C. A. ;
Tefferi, A. .
LEUKEMIA, 2010, 24 (01) :110-114
[7]   Host genetic variation contributes to phenotypic diversity in myeloproliferative disorders [J].
Pardanani, Animesh ;
Fridley, Brooke L. ;
Lasho, Terra L. ;
Gilliland, D. Gary ;
Tefferi, Ayalew .
BLOOD, 2008, 111 (05) :2785-2789
[8]   MPL515 mutations in myeloproliferative and other myeloid disorders:: a study of 1182 patients [J].
Pardanani, Animesh D. ;
Levine, Ross L. ;
Lasho, Terra ;
Pikman, Yana ;
Mesa, Ruben A. ;
Wadleigh, Martha ;
Steensma, David P. ;
Elliott, Michelle A. ;
Wolanskyj, Alexandra R. ;
Hogan, William J. ;
McClure, Rebecca F. ;
Litzow, Mark R. ;
Gilliland, D. Gary ;
Tefferi, Ayalew .
BLOOD, 2006, 108 (10) :3472-3476
[9]   Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival [J].
Tefferi, A. ;
Lasho, T. L. ;
Huang, J. ;
Finke, C. ;
Mesa, R. A. ;
Li, C. Y. ;
Wu, W. ;
Hanson, C. A. ;
Pardanani, A. .
LEUKEMIA, 2008, 22 (04) :756-761
[10]   Classification and diagnosis of myeloproliferative neoplasms: The 2008 World Health Organization criteria and point-of-care diagnostic algorithms [J].
Tefferi, A. ;
Vardiman, J. W. .
LEUKEMIA, 2008, 22 (01) :14-22