Copper-Catalyzed Geminal Difunctionalization of Terminal Alkynes by Splitting Sulfonyl Hydrazones into Two Parts

被引：33
作者：
Sun, Qi
Li, Linge
Liu, Liyan
Guan, Qianqian
Yang, Yu
Zha, Zhenggen
Wang, Zhiyong [1 ]
机构：
[1] Univ Sci & Technol China, Hefei Natl Lab Phys Sci Microscale, CAS Key Lab Soft Matter Chem, Hefei 230026, Anhui, Peoples R China
来源：
ORGANIC LETTERS | 2018年 / 20卷 / 18期
关键词：
VINYL SULFONES; N-TOSYLHYDRAZONES; (E)-VINYL SULFONES; STEREOSELECTIVE-SYNTHESIS; CINNAMIC-ACIDS; SULFUR-DIOXIDE; BOND FORMATION; RADICAL-ADDITION; INHIBITORS; EFFICIENT;
D O I：
10.1021/acs.orglett.8b02268
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A copper(I)-catalyzed geminal difunctionalization of terminal alkynes was developed via a carbene migratory insertion and an addition of a sulfonyl anion to the triple bond at the same time under mild reaction conditions, providing a variety of vinyl sulfones with good yields and excellent stereoselectivities.
引用
收藏
页码：5592 / 5596
页数：5
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