Neurosjogren: An unusual presentation with central nervous system involvement

被引：0

作者：

Essaadouni, L. ^{[1
]}

Jghaimi, F. ^{[1
]}

Kissani, N. ^{[2
]}

机构：

[1] CHU Mohamed VI, Hop Ibn Tofail, Serv Med Interne, Marrakech, Morocco

[2] CHU Mohamed VI, Hop Ibn Tofail, Serv Neurol, Marrakech, Morocco

来源：

REVUE NEUROLOGIQUE | 2010年 / 166卷 / 04期

关键词：

Sjogren's syndrome; Central nervous system; Neurological involvement; MRI; PRIMARY SJOGRENS-SYNDROME; MANIFESTATIONS;

D O I：

10.1016/j.neurol.2009.06.007

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction. - Neurological manifestations in Sjogren's syndrome are variable. The peripheral nervous system is generally involved. We report a rare case of an unusual central neurological manifestation. Case report. - A 54-year-old woman was admitted with headache and tetraparesia. The physical examination revealed a tetrapyramidal syndrome and a bilateral parotidomegaly. The patient's general condition was nevertheless quite good. Brain MRI showed an heterogeneous pontine lesion with multiple nodular formations in the periventricular white matter. Blood tests revealed anti-SSA and anti-SSB antibodies. A labial salivary gland biopsy was grade IV in Chisholm scoring system and Schirmer's test was positive. Conclusion. - A latent Sjogren's syndrome can lead to a wide variety of focal brain MRI abnormalities and should be evoked when the etiology is not clear. (C) 2009 Elsevier Masson SAS. All rights reserved.

引用

页码：443 / 445

页数：3

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