Biological Activities of Quinoline Derivatives

被引：469
作者：
Kumar, Suresh [1 ]
Bawa, Sandhya [1 ]
Gupta, Himanshu [1 ]
机构：
[1] Jamia Hamdard, Fac Pharm, Dept Pharmaceut Chem, New Delhi 110062, India
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2009年 / 9卷 / 14期
关键词：
Quinoline; anticancer; antimycobacterial; anticonvulsant; antibacterial activity; cardiovascular activities; BAYLIS-HILLMAN ADDUCTS; ANTIMICROBIAL ACTIVITY; ANTIRHEUMATIC ACTIVITY; ANTICONVULSANT; CONVENIENT; INHIBITORS; ANILINES; DESIGN; CELL;
D O I：
10.2174/138955709791012247
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Quinoline and its fused heterocyclic derivatives tested with diverse pharmacological activity constitute an important class of compounds for new drug development. Therefore, many researchers have synthesized these compounds as target structures and evaluated their biological activities. The present review provides an in depth view of work done so far on quinolines and its biological activities covering anticancer, antimycobacterial, antimicrobial, anticonvulsant, antiinflamatory and cardiovascular activities.
引用
收藏
页码：1648 / 1654
页数：7
相关论文
共 50 条
  • [41] Synthesis and antimicrobial activities of novel quinoline derivatives carrying 1,2,4-triazole moiety
    Eswaran, Sumesh
    Adhikari, Airody Vasudeva
    Shetty, N. Suchetha
    EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 44 (11) : 4637 - 4647
  • [42] Synthesis and evaluation of the anti-inflammatory activity of quinoline derivatives
    Wen, Xiang
    Wang, Shi-Ben
    Liu, Da-Chuan
    Gong, Guo-Hua
    Quan, Zhe-Shan
    MEDICINAL CHEMISTRY RESEARCH, 2015, 24 (06) : 2591 - 2603
  • [43] Synthesis of Some Heterofunctionalized Penicillanic Acid Derivatives and Investigation of Their Biological Activities
    Demirci, Serpil
    Demirbas, Ahmet
    Ulker, Serdar
    Alpay-Karaoglu, Sengul
    Demirbas, Neslihan
    ARCHIV DER PHARMAZIE, 2014, 347 (03) : 200 - 220
  • [44] A review on recent progress in synthesis and biological activities of thiadiazole and its derivatives
    Ahmad, Suhail
    Alam, Md. Zafer
    Salma, Umme
    Mohasin, Md.
    Rahaman, P. Fazul
    Parveen, Humaira
    Khan, Salman A.
    JOURNAL OF MOLECULAR STRUCTURE, 2024, 1312
  • [45] An Insight into Synthetic Strategies for Schiff Base Derivatives with Diverse Biological Activities
    Singh, Jagseer
    Chawla, Pooja A.
    Akhtar, Md Jawaid
    Kumar, Bhupinder
    MINI-REVIEWS IN ORGANIC CHEMISTRY, 2021, 18 (08) : 1098 - 1126
  • [46] Synthesis and biological activities of novel pyrazolomatrine derivatives
    Kong, Wenlong
    Bao, Yinhe
    Ma, Qianjun
    Xu, Hui
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2018, 28 (20) : 3338 - 3341
  • [47] A COMPREHENSIVE REVIEW ON BENZOTHIAZOLE DERIVATIVES FOR THEIR BIOLOGICAL ACTIVITIES
    Abrol, Shubham
    Bodla, R. B.
    Goswami, Chatinaya
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH, 2019, 10 (07): : 3196 - 3209
  • [48] Synthesis and antimicrobial activities of thiadiazole containing quinoline derivatives
    Dayananda, P.
    Nayak, Janardhana
    D'Souza, Vineetha Telma
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2021, 60 (04): : 633 - 638
  • [49] Quinoline-hydrazone Conjugates: Recent Insights into Synthetic Strategies, Structure-activity Relationship, and Biological Activities
    Kumar, Upendra
    Kumar, Rajnish
    Mazumder, Avijit
    Kumar, Greesh
    LETTERS IN DRUG DESIGN & DISCOVERY, 2024, 21 (14) : 2853 - 2874
  • [50] Biological activities of hydrazone derivatives
    Rollas, Sevim
    Kucukguzel, S. Guniz
    MOLECULES, 2007, 12 (08): : 1910 - 1939
12345