Allelochemical, Eudesmane-Type Sesquiterpenoids from Inula falconeri

被引：12

作者：

Khan, Abdul Latif ^{[1
,2
]}

Hussain, Javid ^{[2
]}

Hamayun, Muhammad ^{[1
]}

Kang, Sang-Mo ^{[1
]}

Kim, Hak-Youn ^{[4
]}

Watanabe, Kazuo N. ^{[3
]}

Lee, In-Jung ^{[1
]}

机构：

[1] Kyungpook Natl Univ, Coll Agr & Life Sci, Sch Plant Biosci, Taegu, South Korea

[2] Kohat Univ Sci & Technol, Kohat 26000, Nwfp, Pakistan

[3] Univ Tsukuba, Ctr Gene Res, Ibaraki, Japan

[4] Keimyung Univ, Coll Environm, Dept Environm Conservat & Disaster Prevent, Taegu, South Korea

来源：

MOLECULES | 2010年 / 15卷 / 03期

关键词：

Inula falconeri; eudesmane sesquiterpenes; allelopathic effect; PAKISTAN;

D O I：

10.3390/molecules15031554

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have identified through bioassay guided isolation an allelochemical, eudesmane-type sesquiterpeniod, 3 beta-caffeoxyl-beta 1,8 alpha-dihydroxyeudesm-4(15)-ene (1), from an endemic plant species growing in the Himalayas. In our search for the bioactive subfraction, the hexane one was highly significant, showing 100% inhibition of lettuce seed growth at 100 ppm while other subfractions (chloroform, ethyl acetate, butanol and water) exhibited inhibitory to stimulatory allelopathic effects. The bioactive hexane subfraction was subjected to chromatographic techniques, using lettuce seeds (Lactuca sativa) as indicator species to reveal the bioactive allelopathic fraction. This resulted in the isolation of compound 1, whose structure was elucidated through NMR techniques. The compound presented 92.34% inhibitory effect on the growth of lettuce at 500 ppm. Further field level experiments may help develop an environmentally friendly herbicide from this lead.

引用

页码：1554 / 1561

页数：8

共 14 条

[1] Herbicidal Activity of Three Sesquiterpene Lactones on Wild Oat (Avena fatua) and Their Possible Mode of Action [J].