Antibiotic prophylaxis in oral and maxillofacial surgery: a systematic review

被引:46
作者
Milic, T. [1 ]
Raidoo, P. [1 ]
Gebauer, D. [1 ]
机构
[1] Royal Perth Hosp, Dept Oral & Maxillofacial Surg, Dept Human Sci, Oral Hlth & Equ, Victoria Sq, Perth, WA 6000, Australia
关键词
antibiotic; maxillofacial; oral; prophylaxis; review; 3RD MOLAR SURGERY; SURGICAL SITE INFECTIONS; CLEAN-CONTAMINATED HEAD; DENTAL IMPLANT FAILURE; DOUBLE-BLIND; ORTHOGNATHIC SURGERY; INFLAMMATORY COMPLICATIONS; FACIAL FRACTURES; PERIOPERATIVE ANTIBIOTICS; MANDIBULAR FRACTURES;
D O I
10.1016/j.bjoms.2020.09.020
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Surgical site infections are a complication of oral and maxillofacial procedures, with the potential for significant morbidity and mortality. Use of preoperative, perioperative, and postoperative antibiotic prophylaxis to reduce the incidence of surgical site infections must be balanced with considerations of a patients' risk of antibiotic-related adverse events. This review aimed to provide evidence-based recommendations for antibiotic prophylaxis. Searches were conducted using MEDLINE, the Cochrane Library, EMBASE, and PUBMED for maxillofacial procedures including: treatment of dental abscesses, extractions, implants, trauma, temporomandibular joints, orthognathics, malignant and benign tumour removal, and bone grafting, limited to articles published since 2000. A total of 98 out of 280 retrieved papers were included in the final analysis. Systematic reviews were assessed using AMSTAR criteria. Randomised controlled trials were assessed for bias using Cochrane Collaborative tools. The overall quality of evidence was assessed using GRADE. Prophylactic antibiotic use is recommended in surgical extractions of third molars, comminuted mandibular fractures, temporomandibular joint replacements, clean-contaminated tumour removal, and complex implants. Prophylactic antibiotic use is not routinely recommended in fractures of the upper or midface facial thirds. Further research is required to provide recommendations in orthognathic, cleft lip, palate, temporomandibular joint surgery, and maxillofacial surgical procedures in medically-compromised patients. Crown Copyright (c) 2020 Published by Elsevier Ltd on behalf of The British Association of Oral and Maxillofacial Surgeons. All rights reserved.
引用
收藏
页码:633 / 642
页数:10
相关论文
共 123 条
[1]   Asepsis during periodontal surgery involving oral implants and the usefulness of peri-operative antibiotics: a prospective, randomized, controlled clinical trial [J].
Abu-Ta'a, Mahmoud ;
Quirynen, Marc ;
Teughels, Wim ;
van Steenberghe, Daniel .
JOURNAL OF CLINICAL PERIODONTOLOGY, 2008, 35 (01) :58-63
[2]   Postoperative antibiotic prophylaxis in mandibular fractures: A preliminary randomized, double-blind, and placebo-controlled clinical study [J].
Abubaker, AO ;
Rollert, MK .
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2001, 59 (12) :1415-1419
[3]  
Ahmad Nabeel, 2012, J Clin Med Res, V4, P1, DOI 10.4021/jocmr658w
[4]   Antibiotic prophylaxis for wound infections in total joint arthroplasty - A systematic review [J].
AlBuhairan, B. ;
Hind, D. ;
Hutchinson, A. .
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 2008, 90B (07) :915-919
[5]   Effectiveness of Antimicrobial Prophylaxis in Preventing the Spread of Infection as a Result of Oral Procedures: A Systematic Review and Meta-Analysis [J].
Alejandra Moreno-Drada, Johana ;
Andres Garcia-Perdomo, Herney .
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2016, 74 (07) :1313-1321
[6]   A systematic review of prophylactic antibiotics in the surgical treatment of maxillofacial fractures [J].
Andreasen, Jens O. ;
Jensen, Simon S. ;
Schwartz, Ole ;
Hillerup, Yoren .
JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2006, 64 (11) :1664-1668
[7]   GRADE guidelines: 14. Going from evidence to recommendations: the significance and presentation of recommendations [J].
Andrews, Jeff ;
Guyatt, Gordon ;
Oxman, Andrew D. ;
Alderson, Phil ;
Dahm, Philipp ;
Falck-Ytter, Yngve ;
Nasser, Mona ;
Meerpohl, Joerg ;
Post, Piet N. ;
Kunz, Regina ;
Brozek, Jan ;
Vist, Gunn ;
Rind, David ;
Akl, Elie A. ;
Schuenemann, Holger J. .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 2013, 66 (07) :719-725
[8]  
Anitua E, 2009, EUR J ORAL IMPLANTOL, V2, P283
[9]  
[Anonymous], 2001, REV ESTOMAT
[10]  
Arduino PG, 2015, EUR J ORAL IMPLANTOL, V8, P143