Clinical features of cardiac lesion in patients with generalized sarcoidosis

被引：0
|
作者：
Popova, E. N. [1 ]
Strizhakov, L. A. [1 ]
Sholomova, V., I [1 ,2 ]
Ponomarev, A. B. [1 ]
Moiseev, S., V [1 ,2 ]
Brovko, M. U. [1 ]
Bondarenko, I. B. [1 ]
Ponomareva, L. A. [1 ]
Fomin, V. V. [1 ]
机构：
[1] IM Sechenov First Moscow State Med Univ, Fac Med, Chair Internal Med 1, Moscow, Russia
[2] Lomonosov Moscow State Univ, Fac Base Med, Dept Internal Med, Moscow, Russia
来源：
TERAPEVTICHESKII ARKHIV | 2018年 / 90卷 / 01期
关键词：
sarcoidosis; extrapulmonary manifestation of sarcoidosis; cardiomyopathy; cardiac rhythm disorder; atherosclerosis; PULMONARY; MORBIDITY; MARKERS; DISEASE; RISK;
D O I：
10.26442/terarkh201890154-59
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The article presents a clinical observation of two patients with generalized sarcoidosis. The woman typical granulomatous changes in the lungs and lymph nodes combined with atrial fibrillation, kidney failure and hereditary thrombophilia, men with atherosclerotic coronary arteries, re-myocardial infarction, cholestasis, tubulointerstitial nephritis. The accession of systemic manifestations was accompanied by increase of level of angiotensin-converting enzyme in the blood serum, morphological examination of lung tissue in both cases there were high histological activity of vasculitis and granulomatous inflammation. Extrapulmonary symptoms regressed when conducting immunosuppressive therapy. Discusses modern aspects of diagnosis of sarcoidosis in clinical practice.
引用
收藏
页码：54 / 59
页数：6
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