Analysis of thromboembolic events in head and neck cancer patients who underwent concurrent chemoradiotherapy with cisplatin

被引:4
|
作者
Cho, Hundo [1 ]
Choi, Jin-Hyuk [1 ]
Kang, Seok Yun [1 ]
Lee, Hyun Woo [1 ]
Choi, Yong Won [1 ]
Kim, Tae-Hwan [1 ]
Ahn, Mi Sun [1 ]
Kim, Chul-Ho [2 ]
Shin, Yoo Seob [2 ]
Jang, Jeon Yeob [2 ]
Oh, Young-Taek [3 ]
Heo, Jaesung [3 ]
Sheen, Seung Soo [4 ]
机构
[1] Ajou Univ, Sch Med, Dept Hematol Oncol, 164 World Cup Ro, Suwon 16499, South Korea
[2] Ajou Univ, Sch Med, Dept Otolaryngol, Suwon, South Korea
[3] Ajou Univ, Sch Med, Dept Radiat Oncol, Suwon, South Korea
[4] Ajou Univ, Sch Med, Dept Pulm & Crit Care Med, Suwon, South Korea
关键词
Head and neck neoplasms; Cisplatin; Chemoradiotherapy; Khorana score; VENOUS THROMBOEMBOLISM; RISK-FACTORS; CHEMOTHERAPY; THROMBOSIS;
D O I
10.3904/kjim.2021.309
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background/Aims: The study investigated the incidence of thromboembolic events (TEE) in head and neck (H&N) cancer patients who received concurrent chemoradiotherapy (CCRT) with cisplatin, and analyzed the factors affecting TEE occur-rence Methods: Two hundred and fifty-seven patients who started CCRT with cisplatin for H&N cancer from January 2005 to De-cember 2019 were analyzed. Results: TEE occurred in five patients, an incidence rate of 1.9%. The 2-, 4-, and 6-month cumulative incidences of TEE were 0.8%, 1.6%, and 1.9%, respectively. Khorana score was the only factor associated with TEE occurrence (p = 0.010). Conclusions: The incidence of TEE in H&N cancer patients who underwent CCRT with cisplatin was relatively low when compared to other types of cancer. However, patients with a high Khorana score require more careful surveillance for possi-ble TEE occurrence.
引用
收藏
页码:653 / 659
页数:7
相关论文
共 50 条
  • [1] Symptom clusters in patients with head and neck cancer receiving concurrent chemoradiotherapy
    Xiao, Canhua
    Hanlon, Alexandra
    Zhang, Qiang
    Ang, Kian
    Rosenthal, David I.
    Nguyen-Tan, P. Felix
    Kim, Harold
    Movsas, Benjamin
    Bruner, Deborah Watkins
    ORAL ONCOLOGY, 2013, 49 (04) : 360 - 366
  • [2] Eustachian Tube Functions in Concurrent Chemoradiotherapy for Head and Neck Cancer Patients
    Ohkoshi, Akira
    Ikeda, Ryoukichi
    Suzuki, Jun
    Yamamoto, Takaya
    Ishii, Ryo
    Higashi, Kenjiro
    Wakamori, Shun
    Nakayama, Yuki
    Nakanome, Ayako
    Ogawa, Takenori
    Katori, Yukio
    INDIAN JOURNAL OF OTOLARYNGOLOGY AND HEAD & NECK SURGERY, 2022, 74 (SUPPL 3) : 6307 - 6312
  • [3] Concurrent chemoradiotherapy with cisplatin and docetaxel for head and neck squamous cell carcinoma
    Kumai, Takumi
    Komatsuda, Hiroki
    Wakisaka, Risa
    Yamaki, Hidekiyo
    Kono, Michihisa
    Hayashi, Ryusuke
    Kishibe, Kan
    Takahara, Miki
    Katada, Akihiro
    Hayashi, Tatsuya
    Harabuchi, Yasuaki
    CLINICAL OTOLARYNGOLOGY, 2022, 47 (01) : 228 - 233
  • [4] Prognostic Significance of Sarcopenia With Inflammation in Patients With Head and Neck Cancer Who Underwent Definitive Chemoradiotherapy
    Cho, Yeona
    Kim, Jun Won
    Keum, Ki Chang
    Lee, Chang Geol
    Jeung, Hei Cheul
    Lee, Ik Jae
    FRONTIERS IN ONCOLOGY, 2018, 8
  • [5] Aspiration Pneumonia After Concurrent Chemoradiotherapy for Head and Neck Cancer
    Xu, Beibei
    Boero, Isabel J.
    Hwang, Lindsay
    Quynh-Thu Le
    Moiseenko, Vitali
    Sanghvi, Parag R.
    Cohen, Ezra E. W.
    Mell, Loren K.
    Murphy, James D.
    CANCER, 2015, 121 (08) : 1303 - 1311
  • [6] Impact of relative cisplatin dose to skeletal muscle mass on adverse events in patients with head and neck cancer undergoing chemoradiotherapy
    Suzuki, Satoshi
    Yokota, Tomoya
    Notsu, Akifumi
    Hamauchi, Satoshi
    Onozawa, Yusuke
    Fushiki, Kunihiro
    Oshima, Kotoe
    Kawakami, Takeshi
    Tsushima, Takahiro
    Yasui, Hirofumi
    Ogawa, Hirofumi
    Onoe, Tsuyoshi
    Kawatani, Keisuke
    Yamazaki, Kentaro
    ONCOLOGIST, 2024, 29 (10) : e1315 - e1323
  • [7] WEEKLY 5-FLUOROURACIL PLUS CISPLATIN FOR CONCURRENT CHEMORADIOTHERAPY IN PATIENTS WITH LOCALLY ADVANCED HEAD AND NECK CANCER
    Lee, Young Joo
    Lee, Chang Geol
    Cho, Byoung Chul
    Kim, Gwi Eon
    Choi, Hye Jin
    Choi, Eun Chang
    Sohn, Joo Hyuk
    Kim, Joo-Hang
    HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2010, 32 (02): : 235 - 243
  • [8] Assessment of quality of life in patients with locally advanced head and neck cancer who received concurrent chemoradiotherapy
    Abd Allah, Hatem
    Zaied, Marwa
    Soliman, Doaa
    ONCOLOGY IN CLINICAL PRACTICE, 2024, : 393 - 398
  • [9] Eustachian Tube Functions in Concurrent Chemoradiotherapy for Head and Neck Cancer Patients
    Akira Ohkoshi
    Ryoukichi Ikeda
    Jun Suzuki
    Takaya Yamamoto
    Ryo Ishii
    Kenjiro Higashi
    Shun Wakamori
    Yuki Nakayama
    Ayako Nakanome
    Takenori Ogawa
    Yukio Katori
    Indian Journal of Otolaryngology and Head & Neck Surgery, 2022, 74 : 6307 - 6312
  • [10] Change of Swallowing in Patients With Head and Neck Cancer After Concurrent Chemoradiotherapy
    Kweon, Sehi
    Koo, Bon Seok
    Jee, Sungju
    ANNALS OF REHABILITATION MEDICINE-ARM, 2016, 40 (06): : 1100 - 1107