Contouring of the Pharyngeal Superior Constrictor Muscle (PSCM). A cooperative study of the Italian Association of Radiation Oncology (AIRO) Head and Neck Group

被引：15

作者：

Alterio, Daniela ^{[1
]}

Ciardo, Delia ^{[1
]}

Preda, Lorenzo ^{[2
]}

Argenone, Angela ^{[3
]}

Caspiani, Orietta ^{[4
]}

Micera, Renato ^{[5
]}

Redda, Maria G. Ruo ^{[6
]}

Russi, Elvio G. ^{[7
]}

Bianchi, Ernestina ^{[8
]}

Orlandi, Ester ^{[9
]}

Bacigalupo, Almalina ^{[10
]}

Busetto, Mario ^{[11
]}

Cante, Domenico ^{[12
]}

Deantonio, Letizia ^{[13
]}

De Sanctis, Vitaliana ^{[14
]}

Franco, Pierfrancesco ^{[15
]}

Lastrucci, Luciana ^{[16
]}

Marucci, Laura ^{[17
]}

Merlotti, Anna ^{[18
]}

Molteni, Marinella ^{[19
]}

Pajar, Fabiola ^{[20
]}

Rampino, Monica ^{[21
]}

Santoro, Luigi ^{[22
]}

Ferrari, Annamaria ^{[1
]}

Bazzani, Federica ^{[1
]}

Caputo, Mariangela ^{[1
]}

Laudati, Antonio ^{[8
]}

Borzillo, Valentina ^{[3
]}

Falivene, Sara ^{[23
]}

Simoni, Nicola ^{[5
]}

Vigo, Federica ^{[5
]}

Iannacone, Eva ^{[9
]}

Reali, Alessia ^{[7
]}

Bonanni, Alessio ^{[4
]}

Leone, Mariavittoria ^{[4
]}

Giannello, Luca ^{[7
]}

Taglianti, Riccardo Vigna ^{[7
]}

Orecchia, Roberto ^{[1
,24
]}

机构：

[1] European Inst Oncol, Adv Radiotherapy Ctr, Milan, Italy

[2] Ist Europeo Oncol, Div Radiol, Milan, Italy

[3] Fdn G Pascale IRCCS Napoli, Isr Nazl Studio & Cura Tumori, Naples, Italy

[4] Osped Fatebenefratelli Isola Tiberina, Rome, Italy

[5] Osped S Maria Nuova, Reggio Emilia, Italy

[6] Univ Turin, Azienda Osped Univ San Luigi Gonzaga Orbassano, I-10124 Turin, Italy

[7] Osped S Croce & Carle, Cuneo, Italy

[8] Osped S Anna Como, Como, Italy

[9] Fdn IRCSS Ist Nazl Tumori, Milan, Italy

[10] IRCSS AOU San Martino IST, Genoa, Italy

[11] Osped Angelo, Venice, Italy

[12] Osped Ivrea, Piemonte, Italy

[13] Univ Piemonte Orientate, SC Radioterapia AOU Maggiore Carita, Novara, Italy

[14] Univ Roma La Sapienza, Dipartimento Sci Med Chirurg & Med Translaz, Rome, Italy

[15] AUSL Valle Aosta, Dept Radiat Oncol, TomoTherapy Unit, Aosta, Italy

[16] Osped S Donato Arezzo, UOC Radioterapia, Arezzo, Italy

[17] Ist Nazl Tumori Regina Elena, Rome, Italy

[18] Azienda Osped Busto Arsizio, Varese, Italy

[19] Osped Circolo Varese, Varese, Italy

[20] Univ Florence, Aziendo Osped Univ Careggi, I-50121 Florence, Italy

[21] Univ Turin, Osped S Giovanni Battista, I-10124 Turin, Italy

[22] Ist Europeo Oncol, Div Epidemiol & Biostat, Milan, Italy

[23] Univ Naples 2, Naples, Italy

[24] Univ Milan, I-20122 Milan, Italy

来源：

RADIOTHERAPY AND ONCOLOGY | 2014年 / 112卷 / 03期

关键词：

Pharyngeal constrictor muscles; Dysphagia; Toxicity; Head and neck cancer; IMRT; INTENSITY-MODULATED RADIOTHERAPY; LOCALLY ADVANCED HEAD; SWALLOWING DYSFUNCTION; CANCER; DYSPHAGIA; CHEMORADIATION; ASPIRATION; TOXICITY; LARYNX;

D O I：

10.1016/j.radonc.2014.05.016

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background and purpose: Irradiation of the Pharyngeal Superior Constrictor Muscle (PSCM) seems to play a crucial role in radiation-related swallowing dysfunctions. Purpose of our study was to quantify operator-related variability in the contouring of PSCM on Computed Tomography (CT) scans and adherence with contours derived from MR images. Materials and methods: Three sets of treatment planning CT and their corresponding MR images were selected. Contouring of the PSCM was performed using both a literature-based method, derived from literature review, and an optimized method, derived from Magnetic Resonance (MR) images thus obtaining "literature-based" and "optimized" contours. Each operator contoured the PSCM on CT scans according to both methods for three times in three different days. Inter- and intra-operator variability and adherence to a contour obtained from MR images (named "MR-derived" contour) were analyzed. Results: Thirty-four operators participated and 612 contours were obtained. Both intra- and inter-operator variability and adherence to the "MR-derived" contour were significantly different between the two methods (p <= 0.05). The "optimized" method showed a lower intra- and inter-operator variability and a higher adherence to the "MR-derived" contour. Conclusions: The "optimized" method ameliorates both operator-related variability and adherence with MR images. (C) 2014 Elsevier Ireland Ltd. All rights reserved.

引用

页码：337 / 342

页数：6

共 20 条

[1] Correlation between dose to the pharyngeal constrictors and patient quality of life and late dysphagia following chemo-IMRT for head and neck cancer [J].

Bhide, Shreerang A. ;

Gulliford, Sarah ;

Kazi, Rehan ;

El-Hariry, Iman ;

Newbold, Kate ;

Harrington, Kevin J. ;

Nutting, Christopher M. .

RADIOTHERAPY AND ONCOLOGY, 2009, 93 (03) :539-544

[2] DOSE TO LARYNX PREDICTS FOR SWALLOWING COMPLICATIONS AFTER INTENSITY-MODULATED RADIOTHERAPY [J].

Caglar, Hale B. ;

Tishler, Roy B. ;

Othus, Megan ;

Burke, Elaine ;

Li, Yi ;

Goguen, Laura ;

Wirth, Lori J. ;

Haddad, Robert I. ;

Norris, Carl M. ;

Court, Laurence E. ;

Aninno, Donald J. ;

Posner, Marshall R. ;

Allen, Aaron M. .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2008, 72 (04) :1110-1118

[3]

Cartmill B, 2012, HEAD NECK

[4] FACTORS ASSOCIATED WITH LONG-TERM DYSPHAGIA AFTER DEFINITIVE RADIOTHERAPY FOR LOCALLY ADVANCED HEAD-AND-NECK CANCER [J].

Caudell, Jimmy J. ;

Schaner, Philip E. ;

Meredith, Ruby F. ;

Locher, Julie L. ;

Nabell, Lisle M. ;

Carroll, William R. ;

Magnuson, J. Scott ;

Spencer, Sharon A. ;

Bonner, James A. .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 73 (02) :410-415

[5] Delineation of organs at risk involved in swallowing for radiotherapy treatment planning [J].

Christianen, Miranda E. M. C. ;

Langendijk, Johannes A. ;

Westerlaan, Henriette E. ;

van de Water, Tara A. ;

Bijl, Hendrik P. .

RADIOTHERAPY AND ONCOLOGY, 2011, 101 (03) :394-402

[6] Normal tissue tolerance to external beam radiation therapy: Larynx and pharynx [J].

Debelleix, C. ;

Pointreau, Y. ;

Lafond, C. ;

Denis, F. ;

Calais, G. ;

Bourhis, J. -H. .

CANCER RADIOTHERAPIE, 2010, 14 (4-5) :301-306

[7] MEASURES OF THE AMOUNT OF ECOLOGIC ASSOCIATION BETWEEN SPECIES [J].

DICE, LR .

ECOLOGY, 1945, 26 (03) :297-302

[8] Evidence-based organ-sparing radiotherapy in head and neck cancer [J].

Dirix, Piet ;

Nuyts, Sandra .

LANCET ONCOLOGY, 2010, 11 (01) :85-91

[9] DYSPHAGIA AFTER CHEMORADIOTHERAPY FOR HEAD-AND-NECK SQUAMOUS CELL CARCINOMA: DOSE-EFFECT RELATIONSHIPS FOR THE SWALLOWING STRUCTURES [J].

Dirix, Piet ;

Abbeel, Sarah ;

Vanstraelen, Bianca ;

Hermans, Robert ;

Nuyts, Sandra .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2009, 75 (02) :385-392

[10] Dysphagia and aspiration after chemoradiotherapy for head-and-neck cancer: Which anatomic structures are affected and can they be spared by IMRT? [J].

Eisbruch, A ;

Schwartz, M ;

Rasch, C ;

Vineberg, K ;

Damen, E ;

Van As, CJ ;

Marsh, R ;

Pameijer, FA ;

Balm, AJM .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2004, 60 (05) :1425-1439

← 1 2 →