Extrarenal Immune-Mediated Disorders Linked with Acute Poststreptococcal Glomerulonephritis: a Systematic Review

被引：13

作者：

Bertola, Elena A. ^{[1
]}

Simonetti, Giacomo D. ^{[1
,2
]}

Del Giorno, Rosaria ^{[3
]}

Giannini, Olivier ^{[4
]}

Fossali, Emilio F. ^{[5
]}

Meoli, Martina ^{[1
]}

Bianchetti, Mario G. ^{[1
,2
]}

Beretta-Piccoli, Benedetta Terziroli ^{[6
,7
]}

Milani, Gregorio P. ^{[8
,9
]}

机构：

[1] Univ Svizzera Italiana, Lugano, Switzerland

[2] Osped San Giovanni Bellinzona, Pediat Inst Southern Switzerland, Bellinzona, Switzerland

[3] Ente Osped Cantonale, Dept Internal Med, Bellinzona, Switzerland

[4] Ente Osped Cantonale, Dept Internal Med, Mendrisio, Switzerland

[5] Fdn IRCCS Ca Granda, Pediat Emergency Dept, Osped Maggiore Policlin, Milan, Italy

[6] Epatoctr Ticino, Via Soldino 5, CH-6900 Lugano, Switzerland

[7] Kings Coll Hosp London, Inst Liver Studies, Mowat Labs, London, England

[8] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Pediat Unit, Milan, Italy

[9] Univ Milan, Dept Clin Sci & Community Hlth, Milan, Italy

来源：

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY | 2019年 / 57卷 / 02期

关键词：

Acute poststreptococcal glomerulonephritis; Acute rheumatic fever; Hemolytic anemia; Henoch-Schonlein purpura; Reactive arthritis; Thrombocytopenia; Uveitis; ACUTE RHEUMATIC-FEVER; HEMOLYTIC-ANEMIA; THROMBOCYTOPENIA; PROTEINURIA; DIAGNOSIS; PSORIASIS; CARDITIS; PURPURA;

D O I：

10.1007/s12016-019-08761-w

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Streptococcus A infections have been associated with immune-mediated sequelae including acute glomerulonephritis, acute rheumatic fever, thrombocytopenia, hemolytic anemia, Henoch-Schonlein purpura, arthritis, uveitis, guttate psoriasis, and erythema nodosum. Available reviews do not report the occurrence of acute poststreptococcal glomerulonephritis in association with one of the mentioned conditions. We performed a systematic review of the literature on extrarenal immune-mediated disorders associated with acute poststreptococcal glomerulonephritis. The principles recommended by the Economic and Social Research Council guidance on the conduct of narrative synthesis and on the Preferred Reporting Items for Meta-Analyses and Systematic Reviews were used. We identified 41 original articles, published after 1965, which reported on 52 patients (34 males and 18 females aged from 1.7 to 57 years, median 9) affected by acute poststreptococcal glomerulonephritis associated with a further poststreptococcal disease: 29 cases with rheumatic fever (17 males and 12 females aged 3.0 to 57, median 17 years), 16 with hematologic diseases such as thrombocytopenia or hemolytic anemia (13 males and 3 females aged 1.8 to 13, median 6.0 years) and seven with Henoch-Schonlein syndrome, reactive arthritis or uveitis (4 males and 3 females aged 1.7 to 14, median 7.0 years). Patients affected by acute poststreptococcal glomerulonephritis associated with acute rheumatic fever were on the average older (P < 0.05) than patients with acute poststreptococcal glomerulonephritis associated with thrombocytopenia, hemolytic anemia, Henoch-Schonlein syndrome, reactive arthritis or uveitis. Five large case series describing 2058 patients affected by acute poststreptococcal glomerulonephritis did not mention its occurrence in association with further immune-mediated disorders. This systematic review points out that acute poststreptococcal glomerulonephritis can be associated, albeit rarely, with rheumatic fever, thrombocytopenia, hemolytic anemia, Henoch-Schonlein syndrome, reactive arthritis, or uveitis.

引用

页码：294 / 302

页数：9

共 65 条

[1] RAPIDLY PROGRESSIVE GLOMERULONEPHRITIS COMPLICATING ACUTE RHEUMATIC-FEVER [J].