Electrooxidative Tandem Cyclization of Activated Alkynes with Sulfinic Acids To Access Sulfonated Indenones

被引：154
作者：
Wen, Jiangwei [1 ,2 ]
Shi, Wenyan [1 ]
Zhang, Fan [1 ]
Liu, Dong [1 ]
Tang, Shan [1 ]
Wang, Huamin [1 ]
Lin, Xiao-Min [2 ]
Lei, Aiwen [1 ]
机构：
[1] Wuhan Univ, Coll Chem & Mol Sci, IAS, Wuhan 430072, Hubei, Peoples R China
[2] Argonne Natl Lab, Ctr Nanoscale Mat, 9700 South Cass Ave, Argonne, IL 60439 USA
来源：
ORGANIC LETTERS | 2017年 / 19卷 / 12期
基金：
中国国家自然科学基金;
关键词：
RADICAL OXIDATIVE ANNULATION; TOPOISOMERASE-I INHIBITORS; BETA-KETO SULFONES; C BOND FORMATION; METAL-FREE; CATALYZED ANNULATION; N-ARYLACRYLAMIDES; COUPLING REACTION; ELECTROCHEMICAL OXIDATION; AROMATIC-SUBSTITUTION;
D O I：
10.1021/acs.orglett.7b01256
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An,electrooxidative direct arylsulfonlylation of yones sulfintc acids via a radical tandem cyclization strategy has been developed for the construction of sulfonated ilicIenones:under oxidant, free conditions. This method provides a simple and efficient approach to prepare various sulfonylindenones in good to,excellent:Tyidds,, demonstrating the tremendous prospect of utilizing electrocatalysis in oxidative coupling, Notably, this reaction could Be easily scaled up with good, efficiency.
引用
收藏
页码：3131 / 3134
页数：4
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