Electrooxidative Tandem Cyclization of Activated Alkynes with Sulfinic Acids To Access Sulfonated Indenones

被引：154

作者：

Wen, Jiangwei ^{[1
,2
]}

Shi, Wenyan ^{[1
]}

Zhang, Fan ^{[1
]}

Liu, Dong ^{[1
]}

Tang, Shan ^{[1
]}

Wang, Huamin ^{[1
]}

Lin, Xiao-Min ^{[2
]}

Lei, Aiwen ^{[1
]}

机构：

[1] Wuhan Univ, Coll Chem & Mol Sci, IAS, Wuhan 430072, Hubei, Peoples R China

[2] Argonne Natl Lab, Ctr Nanoscale Mat, 9700 South Cass Ave, Argonne, IL 60439 USA

来源：

ORGANIC LETTERS | 2017年 / 19卷 / 12期

基金：

中国国家自然科学基金;

关键词：

RADICAL OXIDATIVE ANNULATION; TOPOISOMERASE-I INHIBITORS; BETA-KETO SULFONES; C BOND FORMATION; METAL-FREE; CATALYZED ANNULATION; N-ARYLACRYLAMIDES; COUPLING REACTION; ELECTROCHEMICAL OXIDATION; AROMATIC-SUBSTITUTION;

D O I：

10.1021/acs.orglett.7b01256

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An,electrooxidative direct arylsulfonlylation of yones sulfintc acids via a radical tandem cyclization strategy has been developed for the construction of sulfonated ilicIenones:under oxidant, free conditions. This method provides a simple and efficient approach to prepare various sulfonylindenones in good to,excellent:Tyidds,, demonstrating the tremendous prospect of utilizing electrocatalysis in oxidative coupling, Notably, this reaction could Be easily scaled up with good, efficiency.

引用

页码：3131 / 3134

页数：4

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