One-pot synthesis of benzoazoles via dehydrogenative coupling of aromatic 1,2-diamines/2-aminothiophenol and alcohols using Pd/Cu-MOF as a recyclable heterogeneous catalyst

In this paper we report an efficient synthetic approach for the preparation of the widespread numbers of benzoazoles via dehydrogenative coupling of 1,2-phenylenediamine or 2-aminothiophenol and benzyl alcohols by Pd/Cu-2(BDC)(2)(DABCO)-MOF as new heterogeneous catalyst under solvent-free condition. The catalyst recycled and reused for four times without loss of catalytic activity. The structures of benzoazoles were corroborated spectroscopically (H-1- and C-13 NMR, and elemental analysis) and were confirmed by comparison with reference compounds. A plausible mechanism for this type of reaction is proposed.