A photocaged fluorescent probe for imaging hypochlorous acid in lysosomes

被引：57
作者：
Ren, Mingguang [1 ]
Li, Zihong [1 ]
Nie, Jing [2 ]
Wang, Li [1 ]
Lin, Weiying [1 ]
机构：
[1] Univ Jinan, Inst Fluorescent Probes Biol Imaging, Sch Chem & Chem Engn, Sch Mat Sci & Engn, Jinan 250022, Shandong, Peoples R China
[2] China Univ Min & Technol, Sch Chem Engn & Technol, Xuzhou 221116, Jiangsu, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2018年 / 54卷 / 66期
基金：
中国国家自然科学基金;
关键词：
LIVING CELLS; IN-VIVO; MYELOPEROXIDASE; MITOCHONDRIA; MACROPHAGES; DESIGN;
D O I：
10.1039/c8cc04926b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
By combining the advantages of the photocaging technology and traditional analyte-responsive fluorescent probes, we designed and synthesized the first photocaged lysosomal-targeted fluorescent HOCl probe (PL-HA). The new caged PL-HA probe was capable of remote light-controlled recognition of HOCl in lysosomes.
引用
收藏
页码：9238 / 9241
页数：4
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