Two new depsipeptides from the marine fungus Spicellum roseum

被引：19

作者：

Kralj, Ana

Kehraus, Stefan

Krick, Anja

van Echten-Deckert, Gerhild

Koenig, Gabriele M.

机构：

[1] Univ Bonn, Inst Pharmaceut Biol, D-53115 Bonn, Germany

[2] Univ Bonn, Kekule Inst Organ Chem & Biochem, D-53115 Bonn, Germany

来源：

PLANTA MEDICA | 2007年 / 73卷 / 04期

关键词：

Spicellum roseum; marine-derived fungi; endophyte; Ectyplasia perox; depsipeptide;

D O I：

10.1055/s-2007-967131

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Investigation of the secondary metabolites of the marine-derived fungus Spicellum roseum yielded two new cyclohexadepsipeptides, spicellamide A (1) and spicellamide B (2). The structures of 1 and 2 were determined based on extensive evaluations of NMR and MS data. The absolute configuration was deduced after hydrolysis using Marfey's method, chiral chromatography, as well as NOESY and modeling data.

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页码：366 / 371

页数：6

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