Instructing the Instructor: Tissue-Resident T Cells Activate Innate Immunity

被引:7
|
作者
Sluetter, Bram [1 ]
Harty, John T. [1 ,2 ,3 ]
机构
[1] Univ Iowa, Dept Microbiol, Iowa City, IA 52242 USA
[2] Univ Iowa, Interdisciplinary Grad Program Immunol, Iowa City, IA 52242 USA
[3] Univ Iowa, Dept Pathol, Iowa City, IA 52242 USA
关键词
RM CELLS; MEMORY; SKIN;
D O I
10.1016/j.chom.2014.09.011
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
A small number of tissue-resident memory T cells (T-rm) provide potent protection against infections. Three recent studies by Ariotti et al. (2014), Schenkel et al. (2014a), and Iijima and Iwasaki (2014) report that T-rm rapidly produce cytokines after infection and initiate a tissue-wide anti-viral state by instructing innate immune cells.
引用
收藏
页码:421 / +
页数:4
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