Eosinophils as Biomarkers of Chronic Obstructive Pulmonary Disease Exacerbation Risk Maybe Just for Some?

被引:20
作者
Wedzicha, Jadwiga A. [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Natl Heart & Lung Inst, London, England
基金
英国医学研究理事会;
关键词
BLOOD EOSINOPHILS; COPD EXACERBATIONS; INFLAMMATION;
D O I
10.1164/rccm.201601-0015ED
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
引用
收藏
页码:937 / 938
页数:2
相关论文
共 13 条
[1]   Blood Eosinophils to Direct Corticosteroid Treatment of Exacerbations of Chronic Obstructive Pulmonary Disease A Randomized Placebo-Controlled Trial [J].
Bafadhel, Mona ;
McKenna, Susan ;
Terry, Sarah ;
Mistry, Vijay ;
Pancholi, Mitesh ;
Venge, Per ;
Lomas, David A. ;
Barer, Michael R. ;
Johnston, Sebastian L. ;
Pavord, Ian D. ;
Brightling, Christopher E. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2012, 186 (01) :48-55
[2]   Acute Exacerbations of Chronic Obstructive Pulmonary Disease Identification of Biologic Clusters and Their Biomarkers [J].
Bafadhel, Mona ;
McKenna, Susan ;
Terry, Sarah ;
Mistry, Vijay ;
Reid, Carlene ;
Haldar, Pranabashis ;
McCormick, Margaret ;
Haldar, Koirobi ;
Kebadze, Tatiana ;
Duvoix, Annelyse ;
Lindblad, Kerstin ;
Patel, Hemu ;
Rugman, Paul ;
Dodson, Paul ;
Jenkins, Martin ;
Saunders, Michael ;
Newbold, Paul ;
Green, Ruth H. ;
Venge, Per ;
Lomas, David A. ;
Barer, Michael R. ;
Johnston, Sebastian L. ;
Pavord, Ian D. ;
Brightling, Christopher E. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2011, 184 (06) :662-671
[3]   Relation of sputum inflammatory markers to symptoms and lung function changes in COPD exacerbations [J].
Bhowmik, A ;
Seemungal, TAR ;
Sapsford, RJ ;
Wedzicha, JA .
THORAX, 2000, 55 (02) :114-120
[4]   Impact of Prolonged Exacerbation Recovery in Chronic Obstructive Pulmonary Disease [J].
Donaldson, Gavin C. ;
Law, Martin ;
Kowlessar, Beverly ;
Singh, Richa ;
Brill, Simon E. ;
Allinson, James P. ;
Wedzicha, Jadwiga A. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2015, 192 (08) :943-950
[5]   Human rhinovirus infection during naturally occurring COPD exacerbations [J].
George, Siobhan N. ;
Garcha, Davinder S. ;
Mackay, Alexander J. ;
Patel, Anant R. C. ;
Singh, Richa ;
Sapsford, Raymond J. ;
Donaldson, Gavin C. ;
Wedzicha, Jadwiga A. .
EUROPEAN RESPIRATORY JOURNAL, 2014, 44 (01) :87-96
[6]   Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease. [J].
Hurst, John R. ;
Vestbo, Jorgen ;
Anzueto, Antonio ;
Locantore, Nicholas ;
Muellerova, Hana ;
Tal-Singer, Ruth ;
Miller, Bruce ;
Lomas, David A. ;
Agusti, Alvar ;
MacNee, William ;
Calverley, Peter ;
Rennard, Stephen ;
Wouters, Emiel F. M. ;
Wedzicha, Jadwiga A. .
NEW ENGLAND JOURNAL OF MEDICINE, 2010, 363 (12) :1128-1138
[7]   Infections and airway inflammation in chronic obstructive pulmonary disease severe exacerbations [J].
Papi, Alberto ;
Bellettato, Cinzia Maria ;
Braccioni, Fausto ;
Romagnoli, Micaela ;
Casolari, Paolo ;
Caramori, Gaetano ;
Fabbri, Leonardo M. ;
Johnston, Sebastian L. .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2006, 173 (10) :1114-1121
[8]   Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trials [J].
Pascoe, Steven ;
Locantore, Nicholas ;
Dransfield, Mark T. ;
Barnes, Neil C. ;
Pavord, Ian D. .
LANCET RESPIRATORY MEDICINE, 2015, 3 (06) :435-442
[9]   Blood eosinophils and inhaled corticosteroid/long-acting β-2 agonist efficacy in COPD [J].
Pavord, Ian D. ;
Lettis, Sally ;
Locantore, Nicholas ;
Pascoe, Steve ;
Jones, Paul W. ;
Wedzicha, Jadwiga A. ;
Barnes, Neil C. .
THORAX, 2016, 71 (02) :118-125
[10]   Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease [J].
Seemungal, TAR ;
Donaldson, GC ;
Paul, EA ;
Bestall, JC ;
Jeffries, DJ ;
Wedzicha, JA .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1998, 157 (05) :1418-1422