Determine the Diagnostic Accuracy of (Dipsi Criteria) Non-Fasting Oral Glucose Tolerance Test for Diagnosing Gestational Diabetes Mellitus in Mirpur Azad Jamu Kashmir

Aim: To determine accuracy of 75gm glucose challenge in non-fasting state in gestational diabetes detection (GD) using DIPSI criteria (diabetes in pregnancy study group India). Study place and design: Cross Sectional Descriptive study conducted at DHQ Teaching Hospital Mirpur, AJK Duration of Study: 1st November 2016 to 1st November 2018. Methodology: All pregnant ladies in second and third trimester who were willing for this study after excluding patient with known case of diabetes, multiple pregnancy and active and chronic liver diseases. Total 220 cases were taken 20 cases dropped from study due to vomiting after glucose ingestion. 75gm glucose was given irrespective of last meal after two hours both capillary and venous blood glucose was checked using DIPSI criteria blood sugar more than 140mg were diagnose as gestational diabetes. Result: Out of 200 cases 61 patient has blood sugar (30.5%) more than 140mg and 139 has BSL less than 140mg and were consider negative (69%). 41 turned out to be having GDM (true positive 20%) and required treatment. 20 patients has false positive result (10%). Seven patients having false negative 3.5% and 132 (66%) were true negative. There is no significant difference between plasma and capillary blood glucose. Sensitivity is 85.42% and specificity is 86.84% with positive predictive value of 67.21%. Diagnostic accuracy is 81.5%. Conclusion: Although non fasting OGTT is simple and sensitive procedure so large multicenter trial studies should be encourage on large sample size before recommended as a standard diagnostic test in A Jamu Kashmir.