Early detection of prostate cancer in German urological practice by digital rectal examination and prostate-specific antigen

被引：0
作者：
Luboldt, HJ [1 ]
Hüsing, J [1 ]
Rübben, H [1 ]
Altwein, JE [1 ]
Bichler, KH [1 ]
Czaja, D [1 ]
Fornara, P [1 ]
Jöckel, KH [1 ]
Schalkhäuser, K [1 ]
Weissbach, L [1 ]
Wirth, M [1 ]
机构：
[1] Univ Essen Gesamthsch, Inst Med Informat Epidemiol & Biometrie, Urol Klin & Poliklin, D-45122 Essen, Germany
来源：
UROLOGE A | 2000年 / 39卷 / 04期
关键词：
prostate cancer; early detection; PSA; positive predictive value;
D O I：
10.1007/s001200050365
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
For the early detection of prostate cancer, a patient should undergo digital rectal examination (DRE) and PSA investigation. Followup of increased PSA levels detects nearly 80% of cancers. Positive predictive value of suspicious DRE and PSA is about 50%. Whereas in the first evaluation of this case-finding trial about 70% of the patients had organ-confined cancers, nearly all of the detected cancers in the follow-up investigation were organ confined. The increased number of organ-confined cancers detected in early periodical examinations can lead to a reduction of mortality and morbidity from prostate cancer.
引用
收藏
页码：330 / 333
页数：4
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